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Association between...
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Lund, Lars HKarolinska Institutet,Karolinska Institute, Stockholm, Karolinska University Hospital, Stockholm, Sweden
(författare)
Association between enrolment in a heart failure quality registry and subsequent mortality-a nationwide cohort study.
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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2017-02-23
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John Wiley & Sons,2017
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-139103
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-139103URI
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https://doi.org/10.1002/ejhf.762DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-337762URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136760101URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Funding agencies: Swedish National Board of Health and Welfare; Swedish Association of Local Authorities and Regions; Swedish Society of Cardiology; Swedish Heart-Lung Foundation; Swedish Research Council [2013-23897-104604-23, 523-2014-2336]; Swedish Heart Lung Foundation
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AIMS: Heart failure (HF) quality registries report quality of care but it is unknown whether they improve outcomes. The aims were to assess predictors of enrolment in a HF registry, test the hypothesis that enrolment in a HF registry is associated with reduced mortality, and assess potential explanatory factors for this reduction in mortality, if present.METHODS AND RESULTS: We conducted a nationwide prospective cohort study of patients with new-onset HF registered in the Swedish National Patient Registry (NPR, a mandatory registry of ICD-code diagnoses) with or without concurrent registration in the Swedish Heart Failure Registry (SwedeHF, a voluntary quality reporting registry) 2006-2013. The association between demographics, co-morbidities and medications, and enrolment in the SwedeHF, was assessed using multivariable logistic regression. The association between enrolment in the SwedeHF and all-cause mortality was assessed using multivariable Cox regression, with adjustment for demographics, co-morbidities and medications. A total of 231 437 patients were included, of which 21 888 (9.5%) were in the SwedeHF [age (mean ± standard deviation) 74 ± 13 years; 41% women; 68% inpatients] and 209 549 (90.5%) were not (age 78 ± 12 years, 50% women; 79% inpatients). Selected variables independently associated with enrolment in the SwedeHF were male sex, younger age, higher education, absent co-morbidities and co-morbidity-related medications, and use of HF and cardiovascular medications. Over a median (interquartile range) follow-up of 874 (247-1667) days, there were 13.0 vs. 20.8 deaths per 100 patient-years (P < 0.001). The hazard ratio (95% confidence interval) for death for the SwedeHF yes vs. no was 0.65 (0.63-0.66) crude, and increased to 0.80 (0.78-0.81) after adding demographics, to 0.82 (0.80-0.84) after adding co-morbidities and co-morbidity-related medications, to 0.95 (0.93-0.97) after adding cardiovascular medications, and to 1.04 (1.02-1.07) after adding HF-specific medications.CONCLUSION: Heart failure patients of male sex, younger age, and higher education were more likely to be enrolled in a HF quality registry. Enrolment was associated with reduced all-cause mortality that was explained by demographic differences and better utilization of cardiovascular and HF medications.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Carrero, Juan-JesusKarolinska Institutet,Intervention and Technology, Karolinska Institute, Stockholm, Sweden
(författare)
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Farahmand, BahmanEpi-Consultant, Stockholm, Sweden
(författare)
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Henriksson, Karin M.Uppsala universitet,Kardiovaskulär epidemiologi,Department of Medical Sciences, Uppsala University, Uppsala, Sweden; AstraZeneca RD, Mölndal, Sweden(Swepub:uu)karhe322
(författare)
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Jonsson, ÅsaDivision of Cardiology, County Hospital Ryhov, Jönköping, Sweden,County Hospital Ryhov, Division of Cardiology, Department of Medicine
(författare)
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Jernberg, TomasKarolinska Institutet,Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden
(författare)
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Dahlström, UlfLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US,Linköping University, Department of Cardiology; Linköping University, Department of Medical and Health Sciences(Swepub:liu)ulfda85
(författare)
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Karolinska InstitutetKarolinska Institute, Stockholm, Karolinska University Hospital, Stockholm, Sweden
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Journal of Heart Failure: John Wiley & Sons1388-98421879-0844
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