International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia

The most recent European guidelines and task force reports on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 years ago. Since then, further randomised clinical trials of HAP and VAP have been conducted and new information has become available. Studies of epidemiology, diagnosis, empiric treatment, response to treatment, new antibiotics or new forms of antibiotic administration and disease prevention have changed old paradigms. In addition, important differences between approaches in Europe and the USA have become apparent. The European Respiratory Society launched a project to develop new international guidelines for HAP and VAP. Other European societies, including the European Society of Intensive Care Medicine and the European Society of Clinical Microbiology and Infectious Diseases, were invited to participate and appointed their representatives. The Latin American Thoracic Association was also invited. A total of 15 experts and two methodologists made up the panel. Three experts from the USA were also invited (Michael S. Niederman, Marin Kollef and Richard Wunderink). Applying the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) methodology, the panel selected seven PICO (population-intervention-comparison-outcome) questions that generated a series of recommendations for HAP/VAP diagnosis, treatment and prevention.

Niederman, Michael S.Weill Cornell Med, NY USA (author)
Chastre, JeanGrp Hospital Pitie Salpetriere, France (author)
Ewig, SantiagoEvangel Hospital Herne, Germany; Augusta Hospital Bochum, Germany (author)
Fernandez-Vandellos, PatriciaCIBERES, Spain (author)
Hanberger, HåkanLinköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland(Swepub:liu)hakha84 (author)
Kollef, MarinWashington University, MO USA (author)
Li Bassi, GianluigiUniversity of Barcelona, Spain; CIBERES, Spain (author)
Luna, Carlos M.University of Buenos Aires, Argentina (author)
Martin-Loeches, IgnacioTrinity Coll Dublin, Ireland; CIBERES, Spain (author)
Artur Paiva, J.University of Porto, Portugal; University of Porto, Portugal (author)
Read, Robert C.University of Southampton, England; University of Southampton, England; University of Southampton, England (author)
Rigau, DavidIberoamer Cochrane Centre, Spain (author)
Francois Timsit, JeanParis Diderot University, France; Hop Xavier Bichat, France (author)
Welte, TobiasHannover Medical Sch, Germany; German Centre Lung Research DZL, Germany (author)
Wunderink, RichardNorthwestern University, IL 60611 USA (author)
University of Barcelona, Spain; CIBERES, SpainWeill Cornell Med, NY USA (creator_code:org_t)

In:European Respiratory Journal: EUROPEAN RESPIRATORY SOC JOURNALS LTD50:30903-19361399-3003

By the author/editor: Torres, Antoni; Niederman, Micha ...; Chastre, Jean; Ewig, Santiago; Fernandez-Vandel ...; Hanberger, Håkan; show more...; Kollef, Marin; Li Bassi, Gianlu ...; Luna, Carlos M.; Martin-Loeches, ...; Artur Paiva, J.; Read, Robert C.; Rigau, David; Francois Timsit, ...; Welte, Tobias; Wunderink, Richa ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Respiratory Medi ...

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