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The impact of supra...
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Alhede, ChristinaHerlev Gentofte University Hospital, Denmark
(författare)
The impact of supraventricular ectopic complexes in different age groups and risk of recurrent atrial fibrillation after antiarrhythmic medication or catheter ablation
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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ELSEVIER IRELAND LTD,2018
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-143603
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-143603URI
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https://doi.org/10.1016/j.ijcard.2017.09.208DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Funding Agencies|Hans and Nora Buchards Foundation; Aage and Gerda Henschs Foundation; Jens Anker Andersens Foundation
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Introduction: Supraventricular ectopic complexes (SVEC) are known risk factors of recurrent atrial fibrillation (AF). However, the impact of SVEC in different age groups is unknown. We aimed to investigate the risk of AF recurrence with higher SVEC burden in patients +/- 57 years, respectively, after treatment with antiarrhythmic medication (AAD) or catheter ablation (CA). Methods: In total, 260 patients with LVEF amp;gt;40% and age amp;lt;= 70 years were randomized to AAD (N = 132) or CA (N = 128) as first-line treatment for paroxysmal AF. All patients underwent 7-day Holter monitoring at baseline, and after 3, 6, 12, 18 and 24 months and were categorized according to median age +/- 57 years. We used multi-variate Cox regression analyses and we defined high SVEC burden at 3 months of follow-up as the upper 75th percentile amp;gt;195 SVEC/day. AF recurrence was defined as AF amp;gt;= 1 min, AF-related cardioversion or hospitalization. Results: Age amp;gt;57 years were significantly associated with higher AF recurrence rate after CA (58% vs 36%, p = 0.02). After CA, we observed a higher SVEC burden during follow-up in patients amp;gt;57 years which was not observed in the younger age group treatedwith CA (p = 0.006). High SVEC burden at 3 months after CA was associated with AF recurrence in older patients but not in younger patients (amp;gt;57 years: HR 3.4 [1.4-7.9], p = 0.005). We did not find any age-related differences after AAD. Conclusion: We found that younger and older patients respond differently to CA and that SVEC burden was only associated with AF recurrence in older patients. (C) 2017 Elsevier B.V. All rights reserved.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Lauridsen, Trine K.Herlev Gentofte University Hospital, Denmark
(författare)
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Johannessen, ArneHerlev Gentofte University Hospital, Denmark
(författare)
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Dixen, UlrikHvidovre University Hospital, Denmark
(författare)
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Jensen, Jan S.Herlev Gentofte University Hospital, Denmark
(författare)
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Raatikainen, PekkaHelsinki University Hospital, Finland
(författare)
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Hindricks, GerhardLeipzig University Hospital, Germany
(författare)
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Walfridsson, HåkanLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US(Swepub:liu)hakwa83
(författare)
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Kongstadf, OleLund University Hospital, Sweden
(författare)
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Pehrson, SteenRigshosp, Denmark
(författare)
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Englund, AndersÖrebro University Hospital, Sweden
(författare)
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Hartikainen, JuhaKupio University Hospital, Finland
(författare)
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Hansen, Peter S.Varde Heart Centre, Denmark
(författare)
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Nielsen, Jens C.Aarhus University Hospital, Denmark
(författare)
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Jons, ChristianRigshosp, Denmark
(författare)
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Herlev Gentofte University Hospital, DenmarkHvidovre University Hospital, Denmark
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:International Journal of Cardiology: ELSEVIER IRELAND LTD250, s. 122-1270167-52731874-1754
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Alhede, Christin ...
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Lauridsen, Trine ...
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Dixen, Ulrik
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Jensen, Jan S.
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Kongstadf, Ole
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Pehrson, Steen
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Englund, Anders
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Hansen, Peter S.
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Nielsen, Jens C.
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Jons, Christian
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