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Search: id:"swepub:oai:DiVA.org:liu-146333" > Inflammation och at...

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  • Jonasson, Lena,1956-Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US (author)

Inflammation och ateroskleros – sista pusselbiten är på plats : Inflammation är en aktör vid ateroskleros: nya fynd kan ge ny måltavla för effektiv läkemedelsterapi

  • Article/chapterEnglish2017

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  • Stockholm, Sweden :Läkartidningen Förlag AB,2017
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  • LIBRIS-ID:oai:DiVA.org:liu-146333
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-146333URI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

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  • Inflammation and atherosclerosis - last piece of the puzzle has fallen into place Inflammation is a major component of atherosclerotic lesions and inflammatory biomarkers can be used to predict cardiovascular disease. Still, it has been unclear whether inflammation is a driving force in atherosclerosis, or merely an epiphenomenon. The recently published results of the CANTOS trial shows that treatment with canacinumab, a monoclonal antibody to the proinflammatory cytokine interleukin-1ß, led to a significantly lower rate of recurrent cardiovascular events, compared to placebo. Thus, it establishes beyond doubt that inflammation is a treatable pathogenetic mechanism in atherosclerosis.

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  • Hansson, GöranKarolinska Institutet Department of Medicine Solna - Stockholm, Sweden Karolinska Institutet Department of Medicine Solna - Stockholm, Sweden (author)
  • Linköpings universitetAvdelningen för kardiovaskulär medicin (creator_code:org_t)

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  • In:LäkartidningenStockholm, Sweden : Läkartidningen Förlag AB1140023-72051652-7518

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