SyMRI of the Brain: Rapid Quantification of Relaxation Rates and Proton Density, With Synthetic MRI, Automatic Brain Segmentation, and Myelin Measurement

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Hagiwara, AkifumiDepartment of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (author)

SyMRI of the Brain : Rapid Quantification of Relaxation Rates and Proton Density, With Synthetic MRI, Automatic Brain Segmentation, and Myelin Measurement

Article/chapterEnglish2017

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Lippincott Williams & Wilkins,2017
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LIBRIS-ID:oai:DiVA.org:liu-146343
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-146343URI
https://doi.org/10.1097/RLI.0000000000000365DOI

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Language:English
Summary in:English

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Subject category:for swepub-publicationtype

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Conventional magnetic resonance images are usually evaluated using the image signal contrast between tissues and not based on their absolute signal intensities. Quantification of tissue parameters, such as relaxation rates and proton density, would provide an absolute scale; however, these methods have mainly been performed in a research setting. The development of rapid quantification, with scan times in the order of 6 minutes for full head coverage, has provided the prerequisites for clinical use. The aim of this review article was to introduce a specific quantification method and synthesis of contrast-weighted images based on the acquired absolute values, and to present automatic segmentation of brain tissues and measurement of myelin based on the quantitative values, along with application of these techniques to various brain diseases. The entire technique is referred to as "SyMRI" in this review. SyMRI has shown promising results in previous studies when used for multiple sclerosis, brain metastases, Sturge-Weber syndrome, idiopathic normal pressure hydrocephalus, meningitis, and postmortem imaging.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
SyMRI
synthetic MRI
quantitative MRI
QRAPMASTER
brain
relaxation rates
proton density
automatic brain segmentation
myelin measurement
multiple sclerosis

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Warntjes, Marcel, Jan Bertus,1973-Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US(Swepub:liu)marwa64 (author)
Hori, MasaakiDepartment of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (author)
Andica, ChristinaDepartment of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (author)
Nakazawa, MisakiDepartment of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; |Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan (author)
Kumamaru, Kanako KunishimaDepartment of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (author)
Abe, OsamuDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (author)
Aoki, ShigekiDepartment of Radiology, Juntendo University School of Medicine, Japan (author)
Department of Radiology, Juntendo University School of Medicine, Japan; Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanAvdelningen för kardiovaskulär medicin (creator_code:org_t)

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In:Investigative Radiology: Lippincott Williams & Wilkins52:10, s. 647-6570020-99961536-0210

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