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Interactive Visuali...
Interactive Visualization of 3D Histopathology in Native Resolution
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- Falk, Martin, Dr.rer.nat. 1981- (författare)
- Linköpings universitet,Medie- och Informationsteknik,Tekniska fakulteten,Scientific Visualization Group
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- Ynnerman, Anders, 1963- (författare)
- Linköpings universitet,Medie- och Informationsteknik,Tekniska fakulteten,Scientific Visualization Group
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- Treanor, Darren, 1974- (författare)
- Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Leeds Teaching Hospitals NHS Trust, United Kingdom
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- Lundström, Claes, 1973- (författare)
- Linköpings universitet,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Sectra, Linköping, Sweden
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(creator_code:org_t)
- Institute of Electrical and Electronics Engineers (IEEE), 2019
- 2019
- Engelska.
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Ingår i: IEEE Transactions on Visualization and Computer Graphics. - : Institute of Electrical and Electronics Engineers (IEEE). - 1077-2626 .- 1941-0506 .- 2160-9306. ; 25:1, s. 1008-1017
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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http://liu.diva-port...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- We present a visualization application that enables effective interactive visual analysis of large-scale 3D histopathology, that is, high-resolution 3D microscopy data of human tissue. Clinical work flows and research based on pathology have, until now, largely been dominated by 2D imaging. As we will show in the paper, studying volumetric histology data will open up novel and useful opportunities for both research and clinical practice. Our starting point is the current lack of appropriate visualization tools in histopathology, which has been a limiting factor in the uptake of digital pathology. Visualization of 3D histology data does pose difficult challenges in several aspects. The full-color datasets are dense and large in scale, on the order of 100,000 x 100,000 x 100 voxels. This entails serious demands on both rendering performance and user experience design. Despite this, our developed application supports interactive study of 3D histology datasets at native resolution. Our application is based on tailoring and tuning of existing methods, system integration work, as well as a careful study of domain specific demands emanating from a close participatory design process with domain experts as team members. Results from a user evaluation employing the tool demonstrate a strong agreement among the 14 participating pathologists that 3D histopathology will be a valuable and enabling tool for their work.
Ämnesord
- NATURVETENSKAP -- Data- och informationsvetenskap -- Datavetenskap (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Computer Sciences (hsv//eng)
Nyckelord
- Histology
- Pathology
- Volume Rendering
- Expert Evaluation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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