Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

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Vallejo-Vaz, Antonio J.Imperial Coll London, England (author)

Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

Article/chapterEnglish2018

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ELSEVIER IRELAND LTD,2018
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LIBRIS-ID:oai:DiVA.org:liu-152076
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-152076URI
https://doi.org/10.1016/j.atherosclerosis.2018.08.051DOI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

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Funding Agencies|Pfizer Independent Grant for Learning Change 2014 [16157823]; Amgen; MSD; Sanofi-Aventis
Background and aims: Management of familial hypercholesterolaemia (FH) may vary across different settings due to factors related to population characteristics, practice, resources and/or policies. We conducted a survey among the worldwide network of EAS FHSC Lead Investigators to provide an overview of FH status in different countries. Methods: Lead Investigators from countries formally involved in the EAS FHSC by mid-May 2018 were invited to provide a brief report on FH status in their countries, including available information, programmes, initiatives, and management. Results: 63 countries provided reports. Data on FH prevalence are lacking in most countries. Where available, data tend to align with recent estimates, suggesting a higher frequency than that traditionally considered. Low rates of FH detection are reported across all regions. National registries and education programmes to improve FH awareness/knowledge are a recognised priority, but funding is often lacking. In most countries, diagnosis primarily relies on the Dutch Lipid Clinics Network criteria. Although available in many countries, genetic testing is not widely implemented (frequent cost issues). There are only a few national official government programmes for FH. Under-treatment is an issue. FH therapy is not universally reimbursed. PCSK9-inhibitors are available in similar to 2/3 countries. Lipoprotein-apheresis is offered in similar to 60% countries, although access is limited. Conclusions: FH is a recognised public health concern. Management varies widely across countries, with overall suboptimal identification and under-treatment. Efforts and initiatives to improve FH knowledge and management are underway, including development of national registries, but support, particularly from health authorities, and better funding are greatly needed.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
Familial hypercholesterolaemia; Primary dyslipidaemia; FHSC

Added entries (persons, corporate bodies, meetings, titles ...)

De Marco, MartinaImperial Coll London, England (author)
Stevens, Christophe A. T.Imperial Coll London, England (author)
Akram, AsifLiving Goods, Kenya (author)
Freiberger, TomasCtr Cardiovasc Surg and Transplantat, Czech Republic; Masaryk Univ, Czech Republic (author)
Hovingh, G. KeesAcad Med Ctr, Netherlands (author)
Kastelein, John J. P.Acad Med Ctr, Netherlands (author)
Mata, PedroFdn Hipercolesterolemia Familiar, Spain (author)
Raal, Frederick J.Univ Witwatersrand, South Africa (author)
Santos, Raul D.Univ Sao Paulo, Brazil; Hosp Israelita Albert Einstein, Brazil (author)
Soran, HandreanManchester Univ Hosp NHS Fdn Trust, England (author)
Watts, Gerald F.Univ Western Australia, Australia; Royal Perth Hosp, Australia; FH Australasia Network FHAN, Australia (author)
Abifadel, MarianneSt Joseph Univ, Lebanon (author)
Aguilar-Salinas, Carlos A.Inst Nacl Ciencias Med and Nutr Salvador Zubiran, Mexico (author)
Al-Khnifsawi, MutazAl Qadisiyah Univ, Iraq (author)
AlKindi, Fahad A.Hamad Med Corp, Qatar (author)
Alnouri, FahadPrince Sultan Cardiac Ctr Riyadh, Saudi Arabia (author)
Alonso, RodrigoClin Las Condes, Chile (author)
Al-Rasadi, KhalidSultan Qaboos Univ Hosp, Oman (author)
Al-Sarraf, AhmadKuwait Canc Control Ctr, Kuwait (author)
Ashavaid, Tester F.PD Hinduja Natl Hosp and Med Res Ctr, India (author)
Binder, Christoph J.Med Univ Vienna, Austria (author)
Bogsrud, Martin P.Oslo Univ Hosp, Norway; Oslo Univ Hosp, Norway (author)
Bourbon, MafaldaInst Nacl Saude Doutor Ricardo Jorge, Portugal; Univ Lisbon, Portugal (author)
Bruckert, EricHop La Pitie Salpetriere, France; Hop La Pitie Salpetriere, France (author)
Chlebus, KrzysztofMed Univ Gdansk, Poland; Univ Clin Ctr, Poland (author)
Corral, PabloFASTA Univ, Argentina (author)
Descamps, OlivierCtr Hosp Jolimont, Belgium (author)
Durst, RonenHadassah Hebrew Univ Med Ctr, Israel; Hadassah Hebrew Univ Med Ctr, Israel (author)
Ezhov, MaratMinist Hlth Russian Federat, Russia (author)
Fras, ZlatkoUniv Med Ctr Ljubljana, Slovenia; Univ Ljubljana, Slovenia (author)
Genest, JacquesMcGill Univ, Canada (author)
Groselj, UrhUniv Med Ctr Ljubljana, Slovenia (author)
Harada-Shiba, MarikoNatl Cerebral and Cardiovasc Ctr, Japan (author)
Kayikcioglu, MeralEge Univ, Turkey (author)
Lalic, KatarinaUniv Belgrade, Serbia; Clin Ctr Serbia, Serbia (author)
Lam, Carolyn S. P.Natl Heart Ctr, Singapore; Duke NUS Med Sch, Singapore (author)
Latkovskis, GustavsUniv Latvia, Latvia (author)
Laufs, UlrichUniv Klinikum Leipzig, Germany (author)
Liberopoulos, EvangelosUniv Ioannina, Greece (author)
Lin, JieCapital Med Univ, Peoples R China (author)
Maher, VincentAdv Lipid Management and Res ALMAR Ctr, Ireland (author)
Majano, NelsonHosp Mil Caracas, Venezuela (author)
Marais, A. DavidUniv Cape Town, South Africa; Natl Hlth Lab Serv, South Africa (author)
Maerz, WinfriedHeidelberg Univ, Germany; Med Univ Graz, Austria; Synlab Holding Deutschland GmbH, Germany; Synlab Holding Deutschland GmbH, Germany; D A CH Gesell Pravent Herz Kreislauf Erkrankungen, Germany (author)
Mirrakhimov, ErkinKyrgyz State Med Acad, Kyrgyzstan (author)
Miserez, Andre R.Swiss FH Ctr, Switzerland; Univ Basel, Switzerland (author)
Mitchenko, OlenaNatl Acad Med Sci Ukraine, Ukraine (author)
Nawawi, Hapizah M.Inst Pathol Lab and Forens Med I PPerForM, Malaysia; Univ Teknol Malaysia, Malaysia (author)
Nordestgaard, Borge G.Copenhagen Univ Hosp, Denmark; Copenhagen Univ Hosp, Denmark; Univ Copenhagen, Denmark (author)
Paragh, GyorgyUniv Debrecen, Hungary (author)
Petrulioniene, ZanetaVilnius Univ, Lithuania; Vilnius Univ Hosp Santaros Klin, Lithuania (author)
Pojskic, BelmaCantonal Hosp Zenica, Bosnia and Herceg (author)
Postadzhiyan, ArmanMed Univ Sofia, Bulgaria (author)
Reda, AshrafMenoufia Univ, Egypt; Egyptian Assoc Vernacular Biol and Atherosclerosis, Egypt (author)
Reiner, ZeljkoUniv Zagreb, Croatia (author)
Sadoh, Wilson E.Univ Benin, Nigeria (author)
Sahebkar, AmirhosseinMashhad Univ Med Sci, Iran; Mashhad Univ Med Sci, Iran; Mashhad Univ Med Sci, Iran (author)
Shehab, AbdullahUnited Arab Emirates Univ, U Arab Emirates (author)
Shek, Aleksander B.Minist Hlth Republ Uzbekistan, Uzbekistan (author)
Stoll, MarioHonorary Commiss Cardiovasc Hlth CHSCV, Uruguay (author)
Su, Ta-ChenNatl Taiwan Univ Hosp, Taiwan (author)
Subramaniam, TavintharanAdmiralty Med Ctr, Singapore; Khoo Teck Puat Hosp, Singapore; Khoo Teck Puat Hosp, Singapore (author)
Susekov, Andrey V.Acad Postgrad Med Educ, Russia; Acad Med Sci, Russia (author)
Symeonides, PhivosHippocrateon Private Hosp, Cyprus (author)
Tilney, MyraUniv Malta, Malta; Mater Dei Hosp, Malta (author)
Tomlinson, BrianChinese Univ Hong Kong, Peoples R China (author)
Thanh-Huong, TruongHanoi Med Univ, Vietnam; Bach Mai Hosp, Vietnam (author)
Tselepis, Alexandros D.Univ Ioannina, Greece (author)
Tybjaerg-Hansenb, AnneCopenhagen Univ Hosp, Denmark; Copenhagen Univ Hosp, Denmark; Univ Copenhagen, Denmark; Copenhagen Univ Hosp, Denmark (author)
Vazquez-Cardenas, AlejandraUniv Autonoma Guadalajara, Mexico (author)
Viigimaa, MargusTallinn Univ Technol, Estonia (author)
Vohnout, BranislavSlovak Med Univ, Slovakia (author)
Widen, ElisabethUniv Helsinki, Finland (author)
Yamashita, ShizuyaRinku Gen Med Ctr, Japan; Osaka Univ, Japan (author)
Banach, MaciejMed Univ Lodz, Poland (author)
Gaita, DanUniv Med and Farm Victor Babes Timisoara, Romania (author)
Jiang, LixinNatl Ctr Cardiovasc Dis, Peoples R China (author)
Nilsson, LennartLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US(Swepub:liu)lenni29 (author)
Santos, Lourdes E.Univ Philippines, Philippines (author)
Schunkert, HeribertTech Univ Munich, Germany (author)
Tokgozoglu, LaleHacettepe Univ, Turkey (author)
Car, JosipImperial Coll London, England; Nanyang Technol Univ, Singapore (author)
Catapano, Alberico L.Univ Milan, Italy; IRCCS MultiMed, Italy (author)
Ray, Kausik K.Imperial Coll London, England (author)
Imperial Coll London, EnglandLiving Goods, Kenya (creator_code:org_t)

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By the author/editor: Vallejo-Vaz, Ant ...; De Marco, Martin ...; Stevens, Christo ...; Akram, Asif; Freiberger, Toma ...; Hovingh, G. Kees; show more...; Kastelein, John ...; Mata, Pedro; Raal, Frederick ...; Santos, Raul D.; Soran, Handrean; Watts, Gerald F.; Abifadel, Marian ...; Aguilar-Salinas, ...; Al-Khnifsawi, Mu ...; AlKindi, Fahad A ...; Alnouri, Fahad; Alonso, Rodrigo; Al-Rasadi, Khali ...; Al-Sarraf, Ahmad; Ashavaid, Tester ...; Binder, Christop ...; Bogsrud, Martin ...; Bourbon, Mafalda; Bruckert, Eric; Chlebus, Krzyszt ...; Corral, Pablo; Descamps, Olivie ...; Durst, Ronen; Ezhov, Marat; Fras, Zlatko; Genest, Jacques; Groselj, Urh; Harada-Shiba, Ma ...; Kayikcioglu, Mer ...; Lalic, Katarina; Lam, Carolyn S. ...; Latkovskis, Gust ...; Laufs, Ulrich; Liberopoulos, Ev ...; Lin, Jie; Maher, Vincent; Majano, Nelson; Marais, A. David; Maerz, Winfried; Mirrakhimov, Erk ...; Miserez, Andre R ...; Mitchenko, Olena; Nawawi, Hapizah ...; Nordestgaard, Bo ...; Paragh, Gyorgy; Petrulioniene, Z ...; Pojskic, Belma; Postadzhiyan, Ar ...; Reda, Ashraf; Reiner, Zeljko; Sadoh, Wilson E.; Sahebkar, Amirho ...; Shehab, Abdullah; Shek, Aleksander ...; Stoll, Mario; Su, Ta-Chen; Subramaniam, Tav ...; Susekov, Andrey ...; Symeonides, Phiv ...; Tilney, Myra; Tomlinson, Brian; Thanh-Huong, Tru ...; Tselepis, Alexan ...; Tybjaerg-Hansenb ...; Vazquez-Cardenas ...; Viigimaa, Margus; Vohnout, Branisl ...; Widen, Elisabeth; Yamashita, Shizu ...; Banach, Maciej; Gaita, Dan; Jiang, Lixin; Nilsson, Lennart; Santos, Lourdes ...; Schunkert, Herib ...; Tokgozoglu, Lale; Car, Josip; Catapano, Alberi ...; Ray, Kausik K.; show less...

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