Quantifying the optical properties of turbid media using polarization sensitive hyperspectral imaging (SkinSpect): two-layer optical phantom studies

Quantifying the optical properties of turbid media using polarization sensitive hyperspectral imaging (SkinSpect) : two-layer optical phantom studies

A polarization-sensitive hyperspectral imaging system (SkinSpect) has been built and evaluated using two-layer tissue phantoms, fabricated to mimic the optical properties of melanin in different epidermal thickness and hemoglobin in dermal layers. Multiple tissue-mimicking phantoms with varying top layer thicknesses were measured for optical system calibration and performance testing. Phantom properties were characterized and validated using SkinSpect. The resulting analysis shows that the proposed system is capable of distinguishing and differentiating the layer-dependent absorption spectra and the depths at which this absorption occurs.

MacKinnon, NicholasSpectral Molecular Imaging Inc., USA (författare)
Saager, Rolf B.,1974-Beckman Laser Institute and Medical Clinic, USA(Swepub:liu)rolsa28 (författare)
Durkin, Anthony J.Beckman Laser Institute and Medical Clinic, USA (författare)
Chave, RobertSpectral Molecular Imaging Inc., USA (författare)
Farkas, Daniel L.Spectral Molecular Imaging Inc., USA (författare)
Spectral Molecular Imaging Inc., USABeckman Laser Institute and Medical Clinic, USA (creator_code:org_t)

Ingår i:Proceedings SPIE 9328, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII, 93280A (25 March 2015): SPIE - International Society for Optical Engineering

Av författaren/redakt...: Vasefi, Fartash; MacKinnon, Nicho ...; Saager, Rolf B., ...; Durkin, Anthony ...; Chave, Robert; Farkas, Daniel L ...

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