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Quantifying the optical properties of turbid media using polarization sensitive hyperspectral imaging (SkinSpect) : two-layer optical phantom studies

Vasefi, Fartash (author)
Spectral Molecular Imaging Inc., USA
MacKinnon, Nicholas (author)
Spectral Molecular Imaging Inc., USA
Saager, Rolf B., 1974- (author)
Beckman Laser Institute and Medical Clinic, USA
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Durkin, Anthony J. (author)
Beckman Laser Institute and Medical Clinic, USA
Chave, Robert (author)
Spectral Molecular Imaging Inc., USA
Farkas, Daniel L. (author)
Spectral Molecular Imaging Inc., USA
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Spectral Molecular Imaging Inc, USA Beckman Laser Institute and Medical Clinic, USA (creator_code:org_t)
SPIE - International Society for Optical Engineering, 2015
2015
English.
In: Proceedings SPIE 9328, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII, 93280A (25 March 2015). - : SPIE - International Society for Optical Engineering.
  • Conference paper (peer-reviewed)
Abstract Subject headings
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  • A polarization-sensitive hyperspectral imaging system (SkinSpect) has been built and evaluated using two-layer tissue phantoms, fabricated to mimic the optical properties of melanin in different epidermal thickness and hemoglobin in dermal layers. Multiple tissue-mimicking phantoms with varying top layer thicknesses were measured for optical system calibration and performance testing. Phantom properties were characterized and validated using SkinSpect. The resulting analysis shows that the proposed system is capable of distinguishing and differentiating the layer-dependent absorption spectra and the depths at which this absorption occurs.

Subject headings

NATURVETENSKAP  -- Fysik (hsv//swe)
NATURAL SCIENCES  -- Physical Sciences (hsv//eng)

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Vasefi, Fartash
MacKinnon, Nicho ...
Saager, Rolf B., ...
Durkin, Anthony ...
Chave, Robert
Farkas, Daniel L ...
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NATURAL SCIENCES
NATURAL SCIENCES
and Physical Science ...
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Linköping University

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