id:"swepub:oai:DiVA.org:liu-152372"
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- Olsen Faresjö, ÅshildLinköpings universitet,Avdelningen för samhällsmedicin,Medicinska fakulteten (författare)
Pet exposure in the family during pregnancy and risk for type 1 diabetes : The prospective ABIS study
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
- 2018-08-01
- Wiley-Blackwell Publishing Inc.2018
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:liu-152372
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-152372URI
- https://doi.org/10.1111/pedi.12721DOI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
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Klassifikation
Anmärkningar
- Funding Agencies|Barndiabetesfonden (Swedish Child Diabetes Foundation); Swedish Council for Working Life and Social Research [FAS2004-1775]; Swedish Research Council [K2005-72X-11242-11A, K2008-69X-20826-01-4]; Ostgota Brandstodsbolag; Medical Research Council of Southeast Sweden (FORSS); JDRF Wallenberg Foundation [K 98-99D-12813-01A]
- Background: The autoimmune process later leading to type 1 diabetes (T1D) seems to start very early in life. Different viruses have been suspected to contribute to the development of T1D, some already during pregnancy. As viruses may be hosted by animals and from them transferred to humans we decided to investigate if exposure to pets during pregnancy is related to later development of T1D. Methods: ABIS (All Babies in Southeast Sweden)-is a prospective population-based cohort study of unselected children born in southeast Sweden between Oct first 1997 to Oct first 1999. Parents of 16384 children answered a questionnaire within 3 days after birth including information about exposure to different pets. The ABIS registry has been connected to the National Registry of diagnosis and also the national Registry of Drug prescriptions so we know that 137 children have got T1D, and they were compared with the non-diabetic population. Results: During pregnancy, 45.5% of the mothers had pet animals at home. Most common were cats (25.0%) and dogs (18.7%). Neither exposure to dogs (OR = 1.27, P = 0.23) or cats (OR = 0.81, P = 0.31) were associated to later T1D risks. However, exposure to hamsters increased the T1D risk (OR 4.21, P = 0.0007). In a multiple regression this association remained (P = 0.005) when adjusted for other possible risk factors. Conclusions: Exposure to hamster during pregnancy seems to increase the risk of T1D in the child. One possibility could be infection by virus hosted by the pet.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
- etiology; pet exposure; pregnancy; type 1 diabetes; virus
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Ludvigsson, JohnnyLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus(Swepub:liu)johlu29 (författare)
- Linköpings universitetAvdelningen för samhällsmedicin (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Pediatric Diabetes: Wiley-Blackwell Publishing Inc.19:7, s. 1206-12101399-543X1399-5448
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