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  • Dhanani, Jayesh AFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia. jadhanani@hotmail.com; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia. jadhanani@hotmail.com; Critical Care Research Group, The University of Queensland, Brisbane, Australia (author)

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • 2018-07-11
  • Springer Science and Business Media LLC,2018
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-155996
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-155996URI
  • https://doi.org/10.1186/s40635-018-0180-7DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary drug concentrations with inaccurate dosing schedules potentially leading to therapeutic failure and/or the emergence of antibiotic resistance. We describe a research pathway for studying the pharmacokinetics of a nebulised antibiotic during mechanical ventilation using in vitro methods and ovine models, using tobramycin as the study antibiotic.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Cohen, JeremyFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia (author)
  • Parker, Suzanne LFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia (author)
  • Chan, Hak-KimAdvanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia (author)
  • Tang, PatriciaAdvanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia (author)
  • Ahern, Benjamin JFaculty of Science, School of Veterinary Science, The University of Queensland, Gatton, Australia (author)
  • Khan, AdeelFaculty of Science, School of Veterinary Science, The University of Queensland, Gatton, Australia (author)
  • Bhatt, ManojDepartment of Nuclear Medicine and Specialised PET Services Queensland, Royal Brisbane and Womens Hospital, Herston, Queensland, Australia; School of Medicine, Faculty of Health Sciences, University of Queensland, St Lucia, Queensland, Australia (author)
  • Goodman, StevenDepartment of Nuclear Medicine and Specialised PET Services Queensland, Royal Brisbane and Womens Hospital, Herston, Queensland, Australia (author)
  • Diab, SaraCritical Care Research Group, The University of Queensland, Brisbane, Australia (author)
  • Chaudhary, JiveshCritical Care Research Group, The University of Queensland, Brisbane, Australia (author)
  • Lipman, JeffreyFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia; Faculty of Health, Queensland University of Technology, Brisbane, Australia (author)
  • Wallis, Steven CFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia (author)
  • Barnett, AdrianInstitute of Health and Biomedical Innovation and School of Public Health and Social Work, Queensland University of Technology, Kelvin Grove, Brisbane, Australia (author)
  • Chew, Michelle S,1969-Linköpings universitet,Avdelningen för läkemedelsforskning,Medicinska fakulteten,Region Östergötland, ANOPIVA US(Swepub:liu)micch61 (author)
  • Fraser, John FCritical Care Research Group, The University of Queensland, Brisbane, Australia (author)
  • Roberts, Jason AFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia; Centre for Translational Anti-infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Australia; Department of Pharmacy, Royal Brisbane and Womens Hospital, Brisbane, Australia (author)
  • Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia. jadhanani@hotmail.com; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia. jadhanani@hotmail.com; Critical Care Research Group, The University of Queensland, Brisbane, AustraliaFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia (creator_code:org_t)

Related titles

  • In:Intensive Care Medicine Experimental: Springer Science and Business Media LLC6:12197-425X

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