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A research pathway ...
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Dhanani, Jayesh AFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia. jadhanani@hotmail.com; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia. jadhanani@hotmail.com; Critical Care Research Group, The University of Queensland, Brisbane, Australia
(author)
A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models
- Article/chapterEnglish2018
Publisher, publication year, extent ...
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2018-07-11
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Springer Science and Business Media LLC,2018
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-155996
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-155996URI
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https://doi.org/10.1186/s40635-018-0180-7DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary drug concentrations with inaccurate dosing schedules potentially leading to therapeutic failure and/or the emergence of antibiotic resistance. We describe a research pathway for studying the pharmacokinetics of a nebulised antibiotic during mechanical ventilation using in vitro methods and ovine models, using tobramycin as the study antibiotic.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Cohen, JeremyFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia
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Parker, Suzanne LFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia
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Chan, Hak-KimAdvanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia
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Tang, PatriciaAdvanced Drug Delivery Group, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia
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Ahern, Benjamin JFaculty of Science, School of Veterinary Science, The University of Queensland, Gatton, Australia
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Khan, AdeelFaculty of Science, School of Veterinary Science, The University of Queensland, Gatton, Australia
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Bhatt, ManojDepartment of Nuclear Medicine and Specialised PET Services Queensland, Royal Brisbane and Womens Hospital, Herston, Queensland, Australia; School of Medicine, Faculty of Health Sciences, University of Queensland, St Lucia, Queensland, Australia
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Goodman, StevenDepartment of Nuclear Medicine and Specialised PET Services Queensland, Royal Brisbane and Womens Hospital, Herston, Queensland, Australia
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Diab, SaraCritical Care Research Group, The University of Queensland, Brisbane, Australia
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Chaudhary, JiveshCritical Care Research Group, The University of Queensland, Brisbane, Australia
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Lipman, JeffreyFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia; Faculty of Health, Queensland University of Technology, Brisbane, Australia
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Wallis, Steven CFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia
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Barnett, AdrianInstitute of Health and Biomedical Innovation and School of Public Health and Social Work, Queensland University of Technology, Kelvin Grove, Brisbane, Australia
(author)
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Chew, Michelle S,1969-Linköpings universitet,Avdelningen för läkemedelsforskning,Medicinska fakulteten,Region Östergötland, ANOPIVA US(Swepub:liu)micch61
(author)
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Fraser, John FCritical Care Research Group, The University of Queensland, Brisbane, Australia
(author)
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Roberts, Jason AFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia; Centre for Translational Anti-infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Australia; Department of Pharmacy, Royal Brisbane and Womens Hospital, Brisbane, Australia
(author)
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Faculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia. jadhanani@hotmail.com; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia. jadhanani@hotmail.com; Critical Care Research Group, The University of Queensland, Brisbane, AustraliaFaculty of Medicine, UQ Centre for Clinical Research, The University of Queensland, Brisbane, Australia; Department of Intensive Care Medicine, Royal Brisbane and Womens Hospital, Brisbane, Australia
(creator_code:org_t)
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In:Intensive Care Medicine Experimental: Springer Science and Business Media LLC6:12197-425X
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Dhanani, Jayesh ...
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Cohen, Jeremy
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Parker, Suzanne ...
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Chan, Hak-Kim
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Tang, Patricia
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Ahern, Benjamin ...
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Khan, Adeel
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Bhatt, Manoj
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Goodman, Steven
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Diab, Sara
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Chaudhary, Jives ...
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Lipman, Jeffrey
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Wallis, Steven C
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Barnett, Adrian
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Chew, Michelle S ...
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Fraser, John F
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Roberts, Jason A
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