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Use of non-benzodia...
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Westerlind, Björn,1961-Jönköping University,Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Department of Geriatrics, County Hospital Ryhov, Jönköping, Sweden,HHJ. ARN-J (Aging Research Network - Jönköping),Linköping University Hospital
(författare)
Use of non-benzodiazepine hypnotics is associated with falls in nursing home residents : a longitudinal cohort study
- Artikel/kapitelEngelska2019
Förlag, utgivningsår, omfång ...
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2018-10-19
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Springer,2019
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-156240
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-156240URI
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https://doi.org/10.1007/s40520-018-1056-0DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-42764URI
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https://lup.lub.lu.se/record/d1d13cf9-08e7-4052-93fa-02c31ebcec74URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Funding agencies: Medical Research Council of Southeast Sweden (FORSS); Futurum-Academy of Health and Care, Region Jonkoping County
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BackgroundFalls and related injuries are common among older people, and several drug classes are considered to increase fall risk.AimsThis study aimed to investigate the association between the use of certain drug classes and falls in older nursing home residents in Sweden, and relate these to different age groups.MethodsInformation on falls that occurred in the previous year and regular use of possible fall risk drugs including non-benzodiazepine hypnotics (zopiclone and zolpidem) was collected from 331 nursing home residents during 2008–2011. Over the following 6 months, the occurrence of serious falls, requiring a physician visit or hospital care, was registered. Association between serious falls and drug use was compared between an older (≥ 85 years) and a younger group.ResultsAn increased fall risk (Downton Fall Risk Index ≥ 3) was found in 93% of the study subjects (aged 65–101 years). Baseline data indicated an association between falls that occurred in the previous year and regular use of non-benzodiazepine hypnotics (p = 0.005), but not with the other studied drug classes. During the following 6 months, an association between use of non-benzodiazepine hypnotics and serious falls in the older group (p = 0.017, odds ratio 4.311) was found. No association was found between the other studied drug classes and serious falls.DiscussionThese results indicate an association between falls and the use of non-benzodiazepine hypnotics, compounds that previously have been considered generally well-tolerated in older people.ConclusionsCaution is advocated when using non-benzodiazepine hypnotics regularly in older people living in nursing homes.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Östgren, Carl Johan,1963-Linköpings universitet,Avdelningen för samhällsmedicin,Medicinska fakulteten,Region Östergötland, Vårdcentralen Ödeshög,Department of Medical and Health Sciences, Linköping University, Linköping, Sweden,Linköping University Hospital(Swepub:liu)caros18
(författare)
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Mölstad, Sigvard,1949-Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups(Swepub:lu)med-sm2
(författare)
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Midlöv, PatrikLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Department of Clinical Sciences, Malmö,Faculty of Medicine,Family Medicine and Community Medicine,Lund University Research Groups(Swepub:lu)klin-pmi
(författare)
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Hägg, Staffan,1963-Linköpings universitet,Avdelningen för läkemedelsforskning,Medicinska fakulteten,Region Östergötland, Klinisk farmakologi,Futurum, Jönköping, Region Jönköping County, Sweden,Futurum - Academy for Health and Care(Swepub:liu)staha06
(författare)
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Linköpings universitetAvdelningen för neuro- och inflammationsvetenskap
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Aging Clinical and Experimental Research: Springer31:8, s. 1078-10951594-06671720-8319
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