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Brachial pulse pres...
Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry
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- Bonapace, Stefano (författare)
- Osped Sacro Cuore Don Calabria, Italy
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- Rossi, Andrea (författare)
- Univ Verona, Italy
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- Laroche, Cecile (författare)
- European Soc Cardiol, France
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- Crespo-Leiro, Maria G. (författare)
- Complexo Hosp Univ A Coruna, Spain; Inst Invest Biomed, Spain; Univ A Coruna, Spain; Ctr Invest Red Enfermedades Cardiovasc, Spain
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- Piepoli, Massimo F. (författare)
- AUSL Piacenza, Italy
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- Coats, Andrew J. S. (författare)
- San Raffaele Pisana Sci Inst, Italy
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- Dahlström, Ulf (författare)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Malek, Filip (författare)
- Na Homolce Hosp Cardiovasc Ctr, Czech Republic
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- Macarie, Cezar (författare)
- Inst Urgenta Pentru Boli Cardiovasc CC Iliescu, Romania
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- Temporelli, Pier Luigi (författare)
- Ist Ricovero and Cura Carattere Sci, Italy
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- Maggioni, Aldo P. (författare)
- European Soc Cardiol, France; ANMCO Res Ctr, Italy
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- Tavazzi, Luigi (författare)
- GVM CareandRes, Italy
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(creator_code:org_t)
- 2019-12-09
- 2019
- Engelska.
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Ingår i: ESC Heart Failure. - : WILEY PERIODICALS, INC. - 2055-5822. ; 6:6, s. 1167-1177
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the potential contribution of PP in outlining the individual phenotypes. Methods and results We prospectively evaluated 1-year death and rehospitalization in 4314 patients admitted for acute HF grouped by EF and stratified by their PP level on admission. In HF with reduced (amp;lt; 40%) EF (HFrEF), the highest quartiles of PP had the lowest unadjusted [hazard ratio (HR) 0.77, 95% confidence interval (CI) 0.61-0.98] and adjusted (HR 0.64 0.50-0.82) risk of 1 year all cause death compared to the lowest quartile. Its prognostic impact was partially mediated by systolic blood pressure (SBP). In HF with preserved (amp;gt;= 50%) EF (HFpEF), the intermediate quartile of PP showed the lowest 1 year all cause mortality in unadjusted (HR 0.598, CI 0.416-0.858) and adjusted (HR 0.55, 95% CI 0.388-0.801) models with no relationship with SBP. In a receiver operating characteristic analysis, a combination of PP amp;gt; 60 mmHg and SBP amp;gt; 140 mmHg was associated to a preserved EF with a high performance value. No prognostic significance of PP was found in the HF with mid-range EF subgroup. Conclusions In acute HFrEF, there is an almost linear inverse relation between mortality and PP, partly mediated by SBP. In HFpEF, a J-shaped relationship between mortality and PP was present with a better prognosis at the nadir. A combination of PP amp;gt; 60 mmHg with SBP amp;gt; 140 mmHg may be clinically helpful as marker of a preserved left ventricular EF.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Pulse pressure; Heart Failure; Acute Heart Failure; Prognosis
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Bonapace, Stefan ...
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Rossi, Andrea
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Laroche, Cecile
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Crespo-Leiro, Ma ...
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Piepoli, Massimo ...
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Coats, Andrew J. ...
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visa fler...
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Dahlström, Ulf
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Malek, Filip
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Macarie, Cezar
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Temporelli, Pier ...
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Maggioni, Aldo P ...
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Tavazzi, Luigi
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visa färre...
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