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  • Di Saverio, SalomoneUniv Cambridge, England; Univ Insubria, Italy (author)

Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020-04-15
  • BMC,2020
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-165959
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-165959URI
  • https://doi.org/10.1186/s13017-020-00306-3DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • Background and aims Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and practice patterns worldwide. In July 2015, the World Society of Emergency Surgery (WSES) organized in Jerusalem the first consensus conference on the diagnosis and treatment of AA in adult patients with the intention of producing evidence-based guidelines. An updated consensus conference took place in Nijemegen in June 2019 and the guidelines have now been updated in order to provide evidence-based statements and recommendations in keeping with varying clinical practice: use of clinical scores and imaging in diagnosing AA, indications and timing for surgery, use of non-operative management and antibiotics, laparoscopy and surgical techniques, intra-operative scoring, and peri-operative antibiotic therapy. Methods This executive manuscript summarizes the WSES guidelines for the diagnosis and treatment of AA. Literature search has been updated up to 2019 and statements and recommendations have been developed according to the GRADE methodology. The statements were voted, eventually modified, and finally approved by the participants to the consensus conference and by the board of co-authors, using a Delphi methodology for voting whenever there was controversy on a statement or a recommendation. Several tables highlighting the research topics and questions, search syntaxes, and the statements and the WSES evidence-based recommendations are provided. Finally, two different practical clinical algorithms are provided in the form of a flow chart for both adults and pediatric (< 16 years old) patients. Conclusions The 2020 WSES guidelines on AA aim to provide updated evidence-based statements and recommendations on each of the following topics: (1) diagnosis, (2) non-operative management for uncomplicated AA, (3) timing of appendectomy and in-hospital delay, (4) surgical treatment, (5) intra-operative grading of AA, (6) ,management of perforated AA with phlegmon or abscess, and (7) peri-operative antibiotic therapy.

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  • Podda, MauroCagliari Univ Hosp, Italy (author)
  • De Simone, BelindaMaggiore Hosp Parma, Italy (author)
  • Ceresoli, MarcoUniv Milano Bicocca, Italy (author)
  • Augustin, GoranUniv Hosp Ctr Zagreb, Croatia (author)
  • Gori, AliceMaggiore Hosp, Italy (author)
  • Boermeester, MarjaUniv Amsterdam, Netherlands (author)
  • Sartelli, MassimoMacerata Hosp, Italy (author)
  • Coccolini, FedericoPisa Univ Hosp, Italy (author)
  • Tarasconi, AntonioMaggiore Hosp Parma, Italy (author)
  • Angelis, Nicola deHenri Mondor Univ Hosp, France (author)
  • Weber, Dieter G.Royal Perth Hosp, Australia; Univ Western Australia, Australia (author)
  • Tolonen, MattiUniv Helsinki, Finland (author)
  • Birindelli, AriannaAzienda Socio Sanitaria Terr, Italy (author)
  • Biffl, WalterUniv Hawaii, HI 96822 USA (author)
  • Moore, Ernest E.Denver Hlth Med Ctr, CO USA (author)
  • Kelly, MichaelCanberra Hosp, Australia (author)
  • Soreide, KjetilStavanger Univ Hosp, Norway (author)
  • Kashuk, JeffryUniv Jerusalem, Israel (author)
  • Ten Broek, RichardRadboud Univ Nijmegen, Netherlands (author)
  • Gomes, Carlos AugustoUniv Gen Juiz de Fora, Brazil (author)
  • Sugrue, MichaelLetterkenny Hosp, Ireland (author)
  • Davies, Richard JustinUniv Cambridge, England (author)
  • Damaskos, DimitriosRoyal Infirm Edinburgh NHS Trust, Scotland (author)
  • Leppaniemi, AriRoyal Perth Hosp, Australia; Univ Western Australia, Australia (author)
  • Kirkpatrick, AndrewFoothills Med Ctr, Canada (author)
  • Peitzman, Andrew B.Univ Pittsburgh, PA USA (author)
  • Fraga, Gustavo P.FCM Unicamp, Brazil (author)
  • Maier, Ronald V.Univ Washington, WA 98104 USA (author)
  • Coimbra, RaulUCSD Hlth Syst Hillcrest Campus, CA USA (author)
  • Chiarugi, MassimoPisa Univ Hosp, Italy (author)
  • Sganga, GabrieleUniv Cattolica Sacro Cuore, Italy (author)
  • Pisanu, AdolfoCagliari Univ Hosp, Italy (author)
  • Angelis, Gian Luigi deUniv Parma, Italy (author)
  • Tan, EdwardRadboud Univ Nijmegen, Netherlands (author)
  • Van Goor, HarryRadboud Univ Nijmegen, Netherlands (author)
  • Pata, FrancescoNicola Giannettasio Hosp, Italy; Univ Roma La Sapienza, Italy (author)
  • Di Carlo, IsidoroUniv Catania, Italy (author)
  • Chiara, OsvaldoOsped Niguarda Ca Granda, Italy (author)
  • Litvin, AndreyImmanuel Kant Balt Fed Univ, Russia (author)
  • Campanile, Fabio C.San Giovanni Decollato Andosilla Hosp, Italy (author)
  • Sakakushev, BorisMed Univ, Bulgaria (author)
  • Tomadze, GiaTbilisi State Med Univ, Georgia (author)
  • Demetrashvili, ZazaTbilisi State Med Univ, Georgia (author)
  • Latifi, RifatNew York Med Coll, NY 10595 USA (author)
  • Abu-Zidan, FakriUAE Univ, U Arab Emirates (author)
  • Romeo, OresteBronson Trauma Surg, MI USA (author)
  • Segovia-Lohse, HelmutUniv Nacl Asuncion, Paraguay (author)
  • Baiocchi, GianlucaUniv Brescia, Italy (author)
  • Costa, DavidHosp Univ Alicante, Spain (author)
  • Rizoli, SandroUniv Toronto, Canada (author)
  • Balogh, Zsolt J.John Hunter Hosp, Australia; Univ Newcastle, Australia (author)
  • Bendinelli, CinoJohn Hunter Hosp, Australia; Univ Newcastle, Australia (author)
  • Scalea, ThomasR Adams Cowley Trauma Ctr, MD USA (author)
  • Ivatury, RaoVirginia Commonwealth Univ, VA USA (author)
  • Velmahos, GeorgeHarvard Med Sch, MA 02115 USA (author)
  • Andersson, RolandLinköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten(Swepub:liu)rolan90 (author)
  • Kluger, YoramRambam Hlth Care Campus, Israel (author)
  • Ansaloni, LucaBufalini Hosp, Italy (author)
  • Catena, FaustoMaggiore Hosp Parma, Italy (author)
  • Univ Cambridge, England; Univ Insubria, ItalyCagliari Univ Hosp, Italy (creator_code:org_t)

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  • In:World Journal of Emergency Surgery: BMC15:11749-7922

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