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Epidemiology, patho...
Epidemiology, pathophysiology and contemporary management of cardiogenic shock - a position statement from the Heart Failure Association of the European Society of Cardiology
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- Chioncel, Ovidiu (författare)
- Emergency Inst Cardiovasc Dis Prof CC Iliescu, Romania; Univ Med & Pharm Carol Davila, Romania
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- Parissis, John (författare)
- Attikon Univ Hosp, Greece; Natl Kapodistrian Univ Athens, Greece
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- Mebazaa, Alexandre (författare)
- Univ Paris Diderot, France
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- Thiele, Holger (författare)
- Univ Leipzig, Germany; Heart Inst, Germany
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- Desch, Steffen (författare)
- Univ Leipzig, Germany; Heart Inst, Germany,Berlin Inst Hlth Ctr Regenerat Therapies BCRT, Germany; German Ctr Cardiovasc Res DZHK, Germany; Charite, Germany
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- Bauersachs, Johann (författare)
- Hannover Med Sch, Germany
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- Harjola, Veli-Pekka (författare)
- Univ Helsinki, Finland
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- Antohi, Elena-Laura (författare)
- Emergency Inst Cardiovasc Dis Prof CC Iliescu, Romania; Univ Med & Pharm Carol Davila, Romania
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- Arrigo, Mattia (författare)
- Univ Hosp Zurich, Switzerland
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- Gal, Tuvia B. (författare)
- Rabin Med Ctr, Israel; Tel Aviv Univ, Israel
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- Celutkiene, Jelena (författare)
- Vilnius Univ, Lithuania
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- Collins, Sean P. (författare)
- Vanderbilt Univ, TN 37212 USA
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- DeBacker, Daniel (författare)
- Univ Libre Bruxelles, Belgium
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- Iliescu, Vlad A. (författare)
- Emergency Inst Cardiovasc Dis Prof CC Iliescu, Romania; Univ Med & Pharm Carol Davila, Romania
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- Jankowska, Ewa (författare)
- Wroclaw Med Univ, Poland
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- Jaarsma, Tiny (författare)
- Linköpings universitet,Avdelningen för omvårdnad och reproduktiv hälsa,Medicinska fakulteten,Univ Med Ctr Utrecht, Netherlands
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- Keramida, Kalliopi (författare)
- Natl Kapodistrian Univ Athens, Greece; Attikon Univ Hosp, Greece
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- Lainscak, Mitja (författare)
- Gen Hosp Murska Sobota, Slovenia; Univ Ljubljana, Slovenia
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- Lund, Lars H. (författare)
- Karolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden
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- Lyon, Alexander R. (författare)
- Imperial Coll London, England; Royal Brompton Hosp, England
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- Masip, Josep (författare)
- Univ Barcelona, Spain; Hosp Sanitas CIMA, Spain
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- Metra, Marco (författare)
- Univ Brescia, Italy,Soroka Univ, Israel
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- Miro, Oscar (författare)
- Hosp Clin Barcelona, Spain; Univ Barcelona, Spain
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- Mortara, Andrea (författare)
- Policlin Monza, Italy
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- Mueller, Christian (författare)
- Univ Hosp Basel, Switzerland
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- Mullens, Wilfried (författare)
- Ziekenhuis Oost, Belgium; Hasselt Univ, Belgium
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- Nikolaou, Maria (författare)
- Attikon Univ Hosp, Greece
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- Piepoli, Massimo (författare)
- Univ Parma, Italy; St Anna Sch Adv Studies, Italy
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- Price, Susana (författare)
- Royal Brompton Hosp & Harefield NHS Fdn Trust, England
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- Rosano, Giuseppe (författare)
- St Georges Hosp NHS Trust Univ London, England; Ctr Clin & Basic Res IRCCS San Raffaele Pisana, Italy
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- Vieillard-Baron, Antoine (författare)
- UVSQ, France; Univ Hosp Ambroise Pare, France
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- Weinstein, Jean M. (författare)
- Soroka Univ, Israel
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- Anker, Stefan D. (författare)
- Berlin Inst Hlth Ctr Regenerat Therapies BCRT, Germany; German Ctr Cardiovasc Res DZHK, Germany; Charite, Germany
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- Filippatos, Gerasimos (författare)
- Univ Athens, Greece; Univ Cyprus, Cyprus
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- Ruschitzka, Frank (författare)
- Univ Hosp Zurich, Switzerland
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- Coats, Andrew J. S. (författare)
- IRCCS San Raffaele Pisana, Italy
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- Seferovic, Petar (författare)
- Univ Belgrade, Serbia; Serbian Acad Arts & Sci, Serbia
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(creator_code:org_t)
- 2020-07-16
- 2020
- Engelska.
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Ingår i: European Journal of Heart Failure. - : WILEY. - 1388-9842 .- 1879-0844. ; 22:8, s. 1315-1341
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Cardiogenic shock (CS) is a complex multifactorial clinical syndrome with extremely high mortality, developing as a continuum, and progressing from the initial insult (underlying cause) to the subsequent occurrence of organ failure and death. There is a large spectrum of CS presentations resulting from the interaction between an acute cardiac insult and a patients underlying cardiac and overall medical condition. Phenotyping patients with CS may have clinical impact on management because classification would support initiation of appropriate therapies. CS management should consider appropriate organization of the health care services, and therapies must be given to the appropriately selected patients, in a timely manner, whilst avoiding iatrogenic harm. Although several consensus-driven algorithms have been proposed, CS management remains challenging and substantial investments in research and development have not yielded proof of efficacy and safety for most of the therapies tested, and outcome in this condition remains poor. Future studies should consider the identification of the new pathophysiological targets, and high-quality translational research should facilitate incorporation of more targeted interventions in clinical research protocols, aimed to improve individual patient outcomes. Designing outcome clinical trials in CS remains particularly challenging in this critical and very costly scenario in cardiology, but information from these trials is imperiously needed to better inform the guidelines and clinical practice. The goal of this review is to summarize the current knowledge concerning the definition, epidemiology, underlying causes, pathophysiology and management of CS based on important lessons from clinical trials and registries, with a focus on improving in-hospital management.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Nyckelord
- Cardiogenic shock; Organ dysfunction; Mechanical circulatory support; Multidisciplinary team
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Chioncel, Ovidiu
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Parissis, John
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Mebazaa, Alexand ...
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Thiele, Holger
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Desch, Steffen
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Bauersachs, Joha ...
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visa fler...
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Harjola, Veli-Pe ...
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Antohi, Elena-La ...
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Arrigo, Mattia
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Gal, Tuvia B.
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Celutkiene, Jele ...
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Collins, Sean P.
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DeBacker, Daniel
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Iliescu, Vlad A.
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Jankowska, Ewa
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Jaarsma, Tiny
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Keramida, Kallio ...
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Lainscak, Mitja
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Lund, Lars H.
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Lyon, Alexander ...
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Masip, Josep
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Metra, Marco
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Miro, Oscar
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Mortara, Andrea
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Mueller, Christi ...
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Mullens, Wilfrie ...
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Nikolaou, Maria
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Piepoli, Massimo
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Price, Susana
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Rosano, Giuseppe
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Vieillard-Baron, ...
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Weinstein, Jean ...
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Anker, Stefan D.
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Filippatos, Gera ...
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Ruschitzka, Fran ...
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Coats, Andrew J. ...
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Seferovic, Petar
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