id:"swepub:oai:DiVA.org:liu-170566"
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- Lin, ZijieFudan Univ, Peoples R China (author)
Evaluation and review of ways to differentiate sources of ethanol in postmortem blood
- Article/chapterEnglish2020
Publisher, publication year, extent ...
- 2020-09-17
- SPRINGER,2020
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:liu-170566
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-170566URI
- https://doi.org/10.1007/s00414-020-02415-9DOI
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- Language:English
- Summary in:English
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Notes
- Accurate determination of a persons blood alcohol concentration (BAC) is an important task in forensic toxicology laboratories because of the existence of statutory limits for driving a motor vehicle and workplace alcohol testing regulations. However, making a correct interpretation of the BAC determined in postmortem (PM) specimens is complicated, owing to the possibility that ethanol was produced in the body after death by the action of various micro-organisms (e.g., Candida species) and fermentation processes. This article reviews various ways to establish the source of ethanol in PM blood, including collection and analysis of alternative specimens (e.g., bile, vitreous humor (VH), and bladder urine), the identification of non-oxidative metabolites of ethanol, ethyl glucuronide (EtG) and ethyl sulfate (EtS), the urinary metabolites of serotonin (5-HTOL/5-HIAA), and identification ofn-propanol andn-butanol in blood, which are known putrefaction products. Practical utility of the various biomarkers including specificity and stability is discussed.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Annan medicin och hälsovetenskap Rättsmedicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Other Medical and Health Sciences Forensic Science hsv//eng
- Ethanol analysis; Alternative specimens; Postmortem synthesis; Interpretation; Biomarkers
Added entries (persons, corporate bodies, meetings, titles ...)
- Wang, HaoFudan Univ, Peoples R China (author)
- Jones, A WayneLinköpings universitet,Avdelningen för läkemedelsforskning,Medicinska fakulteten(Swepub:liu)wayjo96 (author)
- Wang, FanglinMinist Publ Secur, Peoples R China (author)
- Zhang, YunfengMinist Publ Secur, Peoples R China (author)
- Rao, YulanFudan Univ, Peoples R China (author)
- Fudan Univ, Peoples R ChinaAvdelningen för läkemedelsforskning (creator_code:org_t)
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- In:International journal of legal medicine: SPRINGER134, s. 2081-20930937-98271437-1596
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