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Radiotherapy-induce...
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Enblom, AnnaLinköpings universitet,Omvårdnad,Hälsouniversitetet
(författare)
Radiotherapy-induced Emesis in Patients Treated with Acupuncture, Sham Acupuncture or Standard Care : Effects of Unspecific Acupuncture Mechanisms
- Artikel/kapitelEngelska2010
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LIBRIS-ID:oai:DiVA.org:liu-17236
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-17236URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:vet swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Background: It is not known if acupuncture or sham reduces radiotherapy-induced emesis more than standard care. Methods: Cancer patients were randomized to verum (skin penetrating) acupuncture (n = 109) in the alleged antiemetic acupuncture point PC6 or sham acupuncture (n = 106) performed with a telescopic nonpenetrating needle at a sham point during the whole radiotherapy period. The verum and sham treated patients were compared to a reference cohort receiving standard care only (n = 62). All patients received radiotherapy over abdominal or pelvic regions. The occurrence of emesis in each group was compared using replies documented in questionnaires after a mean dose of 27 Gray. Findings: Nausea (p=0.001) and vomiting were experienced during the preceding week by 37 and 7%, respectively, in the verum group, 38 and 7% in the sham group and 63 and 15% in the standard care group. The nausea intensity in the acupuncture cohort was lower (78% no nausea, 13% a little, 8% moderate, 1% much) compared to the standard care cohort (52% no nausea, 32% a little, 15% moderate, 2% much) (p=0.002). Almost all the verum and sham treated patients (95%) expected antiemetic effects from their treatment. Patients who expected nausea had increased risk for nausea compared to patients who expected low risk for nausea (relative risk 1.6; 95 % confidence interval 1.2-2.4). Interpretations: Both verum acupuncture and nonpenetrating sham acupuncture seem to reduce nausea and vomiting during radiotherapy, possibly by psychobiological mechanisms related to the extra care and expectancy.
Ämnesord och genrebeteckningar
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Acupuncture therapy
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cancer care
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emesis
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expectations
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placebo
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MEDICINE
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MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Lekander, MatsDepartment of Clinical Neuroscience, Osher Centre for Integrative Medicine
(författare)
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Hammar, MatsLinköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet(Swepub:liu)matha92
(författare)
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Johnsson, AnnaDepartment of Oncology, Division of Physiotherapy, University Hospital, Lund, Sweden
(författare)
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Onelöv, ErikDepartment of Oncology, Division of Clinical Cancer Epidemiology, Karoliniska Institute, Stockholm, Sweden
(författare)
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Ingvar, MartinDepartment of Clinical Neuroscience, Osher Centre for Integrative Medicine
(författare)
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Steineck, GunnarDepartment of Oncology, Division of Clinical Cancer Epidemiology, Karoliniska Institute, Stockholm, Sweden
(författare)
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Börjeson, SussanneLinköpings universitet,Omvårdnad,Hälsouniversitetet,Centre of Surgery and Oncology, Linköping University Hospital, Linköping, Sweden(Swepub:liu)susbo15
(författare)
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Linköpings universitetOmvårdnad
(creator_code:org_t)
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