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Synthesis of nine p...
Synthesis of nine potential synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain from a scalable key intermediate
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- Wu, Xiongyu (author)
- Linköpings universitet,Kemi,Tekniska fakulteten
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- Bopp, Daniel (author)
- Univ Appl Sci & Arts Northwestern Switzerland, Switzerland
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- Wallgren, Jakob (author)
- Linköpings universitet,Kemi,Tekniska fakulteten
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- Dahlén, Johan (author)
- Linköpings universitet,Kemi,Tekniska fakulteten
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- Konradsson, Peter (author)
- Linköpings universitet,Kemi,Tekniska fakulteten
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(creator_code:org_t)
- 2020-12-29
- 2021
- English.
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In: Synthetic Communications. - : TAYLOR & FRANCIS INC. - 0039-7911 .- 1532-2432. ; 51:5, s. 776-785
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https://www.tandfonl...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain are of great interest, and several synthetic methods have been developed for the synthesis of these types of metabolites in the literature, which is either lengthy or inappropriate for upscaling. Herein, a straightforward method has been developed and reported for the synthesis of a key intermediate in four steps with an overall yield of 49% on a multigram scale, and its application in the synthesis of nine potential metabolites of synthetic cannabinoids with a 5F-4OH pentyl side chain.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Keyword
- Key intermediate; metabolite; multigram scale; synthetic cannabinoids
Publication and Content Type
- ref (subject category)
- art (subject category)
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