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An audit of high do...
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Dohlmar, FridaLinköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Medicinsk strålningsfysik
(author)
An audit of high dose-rate prostate brachytherapy treatment planning at six Swedish clinics
- Article/chapterEnglish2021
Publisher, publication year, extent ...
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TERMEDIA PUBLISHING HOUSE LTD,2021
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-174413
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-174413URI
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https://doi.org/10.5114/jcb.2021.103588DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:146074986URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|Radium-hemmets forskningsfonder (Stockholm, Sweden) [161042]; Swedish Cancer SocietySwedish Cancer Society [CAN 2018/622, CAN 2017/1029]
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Purpose: High dose-rate prostate brachytherapy has been implemented in Sweden in the late 1980s and early 1990s in six clinics using the same schedule: 20 Gy in two fractions combined with 50 Gy in 25 fractions with external beam radiation therapy. Thirty years have passed and during these years, various aspects of the treatment process have developed, such as ultrasound-guided imaging and treatment planning system. An audit was conducted, including a questionnaire and treatment planning, which aimed to gather knowledge about treatment planning methods in Swedish clinics. Material and methods: A questionnaire and a treatment planning case (non-anatomical images) were sent to six Swedish clinics, in which high-dose-rate prostate brachytherapy is performed. Treatment plans were compared using dosimetric indices and equivalent 2 Gy doses (EQD(2)). Treatment planning system report was used to compare dwell positions and dwell times. Results: For all the clinics, the planning aim for the target was 10.0 Gy, but the volume to receive the dose differed from 95% to 100%. Dose constraints for organs at risk varied with up to 2 Gy. The dose to 90% of target volume ranged from 10.0 Gy to 11.1 Gy, equivalent to 26.0 Gy EQD(2) and 31.3 Gy EQD(2), respectively. Dose non-homogeneity ratio differed from 0.18 to 0.32 for clinical target volume (CTV) in treatment plans and conformity index ranged from 0.52 to 0.59 for CTV. Conclusions: Dose constraints for the organs at risk are showing a larger variation than that reflected in compared treatments plans. In all treatment plans in our audit, at least 10 Gy was administered giving a total treatment of 102 Gy EQD(2), which is in the upper part of the prescription doses published in the GEC/ESTRO recommendations.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Johansson, SakariasKarolinska Univ Hosp, Sweden
(author)
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Larsson, TorbjörnLinköpings universitet,Tillämpad matematik,Tekniska fakulteten(Swepub:liu)torla64
(author)
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Sandborg, MichaelLinköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Medicinsk strålningsfysik(Swepub:liu)micsa02
(author)
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Carlsson Tedgren, ÅsaKarolinska Institutet,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Medicinsk strålningsfysik,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden(Swepub:liu)asaca90
(author)
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Linköpings universitetAvdelningen för diagnostik och specialistmedicin
(creator_code:org_t)
Related titles
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In:Journal of Contemporary Brachytherapy: TERMEDIA PUBLISHING HOUSE LTD13:1, s. 59-711689-832X2081-2841
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