Sökning: WFRF:(Baturova Maria A.) >
Evolution of P-wave...
Evolution of P-wave indices during long-term follow-up as markers of atrial substrate progression in arrhythmogenic right ventricular cardiomyopathy
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- Baturova, Maria A. (författare)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups,Department of Cardiology, Clinical Sciences, Lund University, Sweden; Research Park, Saint Petersburg State University, Russia
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- Svensson, Anneli, 1972- (författare)
- Linköping University,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- Åström Aneq, Meriam, 1964- (författare)
- Linköping University,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US
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- Svendsen, Jesper H. (författare)
- Department of Cardiology, Centre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,Copenhagen University Hospital
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- Risum, Niels (författare)
- Department of Cardiology, Centre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,Copenhagen University Hospital
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- Sherina, Valeriia (författare)
- Department of Biostatistics and Computational Biology, School of Medicine and Dentistry, University of Rochester Medical Center, USA
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- Bundgaard, Henning (författare)
- Department of Cardiology, Centre for Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,Copenhagen University Hospital
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- Meurling, Carl (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Cardiology, Clinical Sciences, Lund University, Sweden
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- Lundin, Catarina (författare)
- Lund University,Lunds universitet,Genetiska och epigenetiska studier av barnleukemi,Forskargrupper vid Lunds universitet,Genetic and epigenetic studies of pediatric leukemia,Lund University Research Groups,Department of Clinical Genetics and Pathology, Division of Laboratory Medicine, Sweden
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- Carlson, Jonas (författare)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups,Department of Cardiology, Clinical Sciences, Lund University, Sweden
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- Platonov, Pyotr G. (författare)
- Lund University,Lunds universitet,Electrocardiology Research Group - CIEL,Forskargrupper vid Lunds universitet,Lund University Research Groups,Department of Cardiology, Clinical Sciences, Lund University, Sweden
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(creator_code:org_t)
- 2021-03-04
- 2021
- Engelska.
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Ingår i: Europace. - : Oxford University Press. - 1099-5129 .- 1532-2092. ; 23:Supplement_1, s. i29-i37
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression.METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according to 2010 Task Force criteria [34% females, median age 41 (inter-quartile range 30-55) years]. All available sinus rhythm ECGs (n = 1504) were extracted from the regional electronic ECG databases and automatically processed using Glasgow algorithm. P-wave duration, P-wave area, P-wave frontal axis, and prevalence of abnormal P terminal force in lead V1 (aPTF-V1) were assessed and compared at ARVC diagnosis, 10 years before and up to 15 years after diagnosis.Prior to ARVC diagnosis, none of the P-wave indices differed significantly from the data at ARVC diagnosis. After ascertainment of ARVC diagnosis, P-wave area in lead V1 decreased from -1 to -30 µV ms at 5 years (P = 0.002). P-wave area in lead V2 decreased from 82 µV ms at ARVC diagnosis to 42 µV ms 10 years after ARVC diagnosis (P = 0.006). The prevalence of aPTF-V1 increased from 5% at ARVC diagnosis to 18% by the 15th year of follow-up (P = 0.004). P-wave duration and frontal axis did not change during disease progression.CONCLUSION: Initial ARVC progression was associated with P-wave flattening in right precordial leads and in later disease stages an increased prevalence of aPTF-V1 was seen.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Arrhythmogenic cardiomyopathy
- Atrial fibrillation
- P-terminal force in lead V1
- P-wave area in lead V1
- P-wave area in lead V2
- Arrhythmogenic cardiomyopathy
- Atrial fibrillation
- P-terminal force in lead V1
- P-wave area in lead V1
- P-wave area in lead V2
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Europace
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Baturova, Maria ...
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Svensson, Anneli ...
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Åström Aneq, Mer ...
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Svendsen, Jesper ...
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Risum, Niels
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Sherina, Valerii ...
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Bundgaard, Henni ...
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Meurling, Carl
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Lundin, Catarina
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Carlson, Jonas
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Platonov, Pyotr ...
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