Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:liu-176872" > Mortality trends am...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Strålin, KristofferKarolinska Institutet,Karolinska Univ Hosp, Sweden; Karolinska Inst, Sweden; Swedens Reg Collaborat, Sweden (author)

Mortality trends among hospitalised COVID-19 patients in Sweden : A nationwide observational cohort study

Article/chapterEnglish2021

Publisher, publication year, extent ...

Elsevier,2021
electronicrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:liu-176872
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-176872URI
https://doi.org/10.1016/j.lanepe.2021.100054DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:154377093URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Funding Agencies|Swedens National Board of Health and Welfare
Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVID-19 in Sweden, using nationwide data compiled by the Swedish National Board of Health and Welfare. Methods: Observational cohort study where all patients hospitalised in Sweden between March 1 and September 30, 2020, with SARS-CoV-2 RNA positivity 14 days before to 5 days after admission and a discharge code for COVID-19 were included. Outcome was 60-day all-cause mortality. Patients were categorised according to month of hospital admission. Poisson regression was used to estimate the relative risk of death by month of admission, adjusting for, age, sex, comorbidities, care dependency, country of birth, healthcare region, and Simplified Acute Physiology, version 3 (patients in intensive care units; ICU). Findings: A total of 17,140 patients were included, of which 2943 died within 60 days of admission. The overall 60-day mortality was thus 17.2% (95% CI, 16.6%-17.7%), and it decreased from 24.7% (95% CI, 23.0%-26.5%) in March to 10.4% (95% CI, 8.9%-12.1%) post-wave (July-September). Adjusted relative risk (RR) of death was 0.46 (95% CI, 0.39-0.54) post-wave, using March as reference. Corresponding RR for patients not admitted to ICU and those admitted to ICU were 0.49 (95% CI, 0.42-0.59) and 0.49 (95% CI, 0.33-0.72), respectively. The proportion of patients admitted to ICU decreased from 19.4% (95% CI, 17.9%-21.1%) in the March cohort to 8.9% (95% CI, 7.5%-10.6%) post-wave. Interpretation: There was a gradual decline in mortality during the spring of 2020 in Swedish hospitalised COVID-19 patients, independent of baseline patient characteristics. Future research is needed to explain the reasons for this decline. The changing COVID-19 mortality should be taken into account when management and results of studies from the first pandemic wave are evaluated. (C) 2021 The Authors. Published by Elsevier Ltd.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

Wahlström, ErikNatl Board Hlth & Welf, Sweden (author)
Walther, StenLinköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland,Varmland Cty Council, Sweden(Swepub:liu)stewa50 (author)
Bennet-Bark, Anna M.Natl Board Hlth & Welf, Sweden (author)
Heurgren, MonaNatl Board Hlth & Welf, Sweden (author)
Lindén, ThomasNatl Board Hlth & Welf, Sweden (author)
Holm, JohannaNatl Board Hlth & Welf, Sweden (author)
Hanberger, HåkanLinköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland(Swepub:liu)hakha84 (author)
Karolinska InstitutetKarolinska Univ Hosp, Sweden; Karolinska Inst, Sweden; Swedens Reg Collaborat, Sweden (creator_code:org_t)

Related titles

In:The Lancet Regional Health: Elsevier42666-7762

Internet link

Find in a library

The Lancet Regional Health (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Strålin, Kristof ...; Wahlström, Erik; Walther, Sten; Bennet-Bark, Ann ...; Heurgren, Mona; Lindén, Thomas; show more...; Holm, Johanna; Hanberger, Håkan; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

Articles in the publication: The Lancet Regio ...

By the university: Linköping University; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se