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Epidemiology of ent...
Epidemiology of enteric virus infections in children living in the Amazon region
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- Olivares, Alberto Ignacio Olivares (författare)
- Fiocruz MS, Brazil; Fiocruz MS, Brazil
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- Leitao, Gabriel Azevedo Alves (författare)
- Fiocruz MS, Brazil; Fiocruz MS, Brazil
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- Pimenta, Yan Cardoso (författare)
- Fiocruz MS, Brazil; Fiocruz MS, Brazil
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- Cantelli, Carina Pacheco (författare)
- Fiocruz MS, Brazil
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- Fumian, Tulio Machado (författare)
- Fiocruz MS, Brazil
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- Fialho, Alexandre Madi (författare)
- Fiocruz MS, Brazil
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- da Silva e Mouta Junior, Sergio (författare)
- Fiocruz MS, Brazil
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- Delgado, Isabella Fernandes (författare)
- Fiocruz MS, Brazil
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- Nordgren, Johan (författare)
- Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
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- Svensson, Lennart (författare)
- Karolinska Institutet,Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
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- Miagostovich, Marize Pereira (författare)
- Fiocruz MS, Brazil
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- Leite, Jose Paulo Gagliardi (författare)
- Fiocruz MS, Brazil
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- Moraes, Marcia Terezinha Baroni de (författare)
- Fiocruz MS, Brazil
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(creator_code:org_t)
- Elsevier Science Ltd, 2021
- 2021
- Engelska.
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Ingår i: International Journal of Infectious Diseases. - : Elsevier Science Ltd. - 1201-9712 .- 1878-3511. ; 108, s. 494-502
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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http://www.ijidonlin...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
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- Objectives: To verify the frequency of viruses causing acute gastroenteritis (AGE) in association with the histo-blood group antigen (HBGA) and Rotarix (TM) vaccination coverage in children from the Amazon region. Design: Fecal and saliva samples were collected from children with AGE (n = 485) and acute respiratory infection (ARI) (n = 249) clinical symptoms. Rotavirus A (RVA), norovirus, human adenovirus (HAdV), and sapovirus (SaV) were verified in feces by molecular detection. Saliva samples were used for HBGA phenotyping/FUT3 genotyping. Blood group types, clinical aspects and Rotarix (TM) RVA vaccination data were recorded. Results: Norovirus remained the most prevalently detected cause of AGE (38%, 184/485 and ARI 21.3%, 53/249). High HAdV frequencies were observed in AGE children (28.6%, 139/485) and ARI children (37.3%, 93/249). RVA was the third most prevalent virus causing AGE (22.7%, 110/485 and ARI 19.3%, 48/249) and a low RV1 coverage (61%, 448/734) was verified. The SaV frequencies were lower (7.2%, 35/485 for AGE and 6.8%, 17/249 for ARI). Secretor children were HBGA susceptible to HAdV infection (OR 1.5, 95% CI 1.0-2.3; P = 0.04) but not to RVA, norovirus or SaV infection. Conclusions: Norovirus could be considered the main etiological agent of AGE. No association was verified for HBGA susceptibility to RVA, norovirus and SaV. Secretor children showed a slight susceptibility to HAdV infection and the Le (a-b-) heterogeneous SNPs on the FUT3 gene. (C) 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Rotavirus A; Norovirus; Human adenovirus; Sapovirus; Histo-blood group antigens; Amazon
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Olivares, Albert ...
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Leitao, Gabriel ...
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Pimenta, Yan Car ...
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Cantelli, Carina ...
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Fumian, Tulio Ma ...
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Fialho, Alexandr ...
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da Silva e Mouta ...
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Delgado, Isabell ...
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Nordgren, Johan
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Svensson, Lennar ...
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Miagostovich, Ma ...
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Leite, Jose Paul ...
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Moraes, Marcia T ...
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