Search: id:"swepub:oai:DiVA.org:liu-179167" >
Admission screening...
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Garpvall, K.Karolinska Inst, Sweden
(author)
Admission screening and cohort care decrease carbapenem resistant enterobacteriaceae in Vietnamese pediatric ICUs
- Article/chapterEnglish2021
Publisher, publication year, extent ...
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2021-08-30
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BMC,2021
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electronicrdacarrier
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LIBRIS-ID:oai:DiVA.org:liu-179167
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-179167URI
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https://doi.org/10.1186/s13756-021-00994-9DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:147503539URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|Karolinska InstituteKarolinska Institutet; Swedish Foundation for International Cooperation in Research and Higher Education (STINT) [SG 2015-5972]; Swedish research council (VR)Swedish Research Council [330-2014-6356]; EU Marie CurieEuropean Commission; SIDA
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Objectives To assess if admission screening for Carbapenem Resistant Enterobacteriaceae (CRE) and cohort care can reduce CRE acquisition (CRE colonization during hospital stay), Hospital Acquired Infections (HAI), hospital-stay, mortality, and costs in three Intensive Care Units (ICUs) at the Vietnamese National Childrens Hospital. Method CRE screening using rectal swabs and ChromIDCarbas elective culture at admission and if CRE negative, once weekly. Patients were treated in cohorts based on CRE colonization status. Results CRE colonization at baseline point-prevalence screening was 76.9% (103/134). Of 941 CRE screened at admission, 337 (35.8%) were CREpos. 694 patients met inclusion criteria. The 244 patients CRE negative at admission and screened > 2 times were stratified in 8 similar size groups (periods), based on time of admission. CRE acquisition decreased significant (OR - 3.2, p < 0.005) from 90% in period 2 (highest) to 48% in period 8 (last period). Patients with CRE acquisition compared to no CRE acquisition had a significantly higher rate of culture confirmed HAI, n = 20 (14%) vs. n = 2 (2%), longer hospital stays, 3.26 vs. 2.37 weeks, and higher total treatment costs, 2852 vs. 2295 USD. Conclusion Admission CRE screening and cohort care in pediatric ICUs significantly decreased CRE acquisition, cases of HAI and duration of hospital-stay.
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Duong, VVietnam Natl Childrens Hosp, Vietnam
(author)
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Linnros, S.Karolinska Inst, Sweden
(author)
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Quoc, T. N.Vietnam Natl Childrens Hosp, Vietnam
(author)
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Mucchiano, D.Karolinska Inst, Sweden
(author)
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Modeen, S.Karolinska Inst, Sweden
(author)
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Lagercrantz, L.Karolinska Institutet
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Edman, A.Karolinska Inst, Sweden
(author)
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Le, N. K.Vietnam Natl Childrens Hosp, Vietnam; Training & Res Acad Collaborat TRAC, Vietnam; Res Inst Child Hlth, Vietnam
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Huong, T.Vietnam Natl Childrens Hosp, Vietnam
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Hoang, N. T. B.Vietnam Natl Childrens Hosp, Vietnam
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Le, H. T.Vietnam Natl Childrens Hosp, Vietnam
(author)
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Khu, D. TkVietnam Natl Childrens Hosp, Vietnam; Training & Res Acad Collaborat TRAC, Vietnam
(author)
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Tran, D. M.Vietnam Natl Childrens Hosp, Vietnam; Res Inst Child Hlth, Vietnam
(author)
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Phuc, P. H.Vietnam Natl Childrens Hosp, Vietnam; Training & Res Acad Collaborat TRAC, Vietnam; Res Inst Child Hlth, Vietnam
(author)
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Hanberger, HåkanLinköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland,Training & Res Acad Collaborat TRAC, Vietnam(Swepub:liu)hakha84
(author)
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Olson, L.Karolinska Inst, Sweden; Training & Res Acad Collaborat TRAC, Vietnam; Karolinska Inst, Sweden
(author)
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Larsson, M.Karolinska Institutet
(author)
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Karolinska Inst, SwedenVietnam Natl Childrens Hosp, Vietnam
(creator_code:org_t)
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In:Antimicrobial Resistance and Infection Control: BMC10:12047-2994
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Garpvall, K.
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Duong, V
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Linnros, S.
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Quoc, T. N.
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Mucchiano, D.
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Modeen, S.
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Lagercrantz, L.
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Edman, A.
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Le, N. K.
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Huong, T.
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Hoang, N. T. B.
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Le, H. T.
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Khu, D. Tk
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Tran, D. M.
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Phuc, P. H.
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Hanberger, Håkan
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Olson, L.
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Larsson, M.
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Antimicrobial Re ...
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Linköping University
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Karolinska Institutet