RF Remote Blood Glucose Sensor and a Microfluidic Vascular Phantom for Sensor Validation

Yunos, Muhammad Farhan Affendi MohamadInt Islamic Univ Malaysia, Malaysia (författare)

Diabetes has become a major health problem in society. Invasive glucometers, although precise, only provide discrete measurements at specific times and are unsuitable for long-term monitoring due to the injuries caused on skin and the prohibitive cost of disposables. Remote, continuous, self-monitoring of blood sugar levels allows for active and better management of diabetics. In this work, we present a radio frequency (RF) sensor based on a stepped impedance resonator for remote blood glucose monitoring. When placed on top of a human hand, this RF interdigital sensor allows detection of variation in blood sugar levels by monitoring the changes in the dielectric constant of the material underneath. The designed stepped impedance resonator operates at 3.528 GHz with a Q factor of 1455. A microfluidic device structure that imitates the blood veins in the human hand was fabricated in PDMS to validate that the sensor can measure changes in glucose concentrations. To test the RF sensor, glucose solutions with concentrations ranging from 0 to 240 mg/dL were injected into the fluidic channels and placed underneath the RF sensor. The shifts in the resonance frequencies of the RF sensor were measured using a network analyzer via its S-11 parameters. Based on the change in resonance frequencies, the sensitivity of the biosensor was found to be 264.2 kHz/mg center dot dL(-1) and its LOD was calculated to be 29.89 mg/dL.

NATURVETENSKAP Biologi Biokemi och molekylärbiologi hsv//swe
NATURAL SCIENCES Biological Sciences Biochemistry and Molecular Biology hsv//eng
blood glucose monitoring; diabetes; non-invasive sensor; PDMS; vascular phantom; glucometer; RF sensor

Manczak, RemiUniv Limoges, France (författare)
Guines, CyrilUniv Limoges, France (författare)
Mansor, Ahmad Fairuzabadi MohdInt Islamic Univ Malaysia, Malaysia (författare)
Mak, Wing CheungLinköpings universitet,Sensor- och aktuatorsystem,Tekniska fakulteten(Swepub:liu)winma81 (författare)
Khan, SherozOnaizah Coll Engn, Saudi Arabia (författare)
Ramli, Noor AmalinaInt Islamic Univ Malaysia, Malaysia (författare)
Pothier, ArnaudUniv Limoges, France (författare)
Nordin, Anis NurashikinInt Islamic Univ Malaysia, Malaysia (författare)
Int Islamic Univ Malaysia, MalaysiaUniv Limoges, France (creator_code:org_t)

Av författaren/redakt...: Yunos, Muhammad ...; Manczak, Remi; Guines, Cyril; Mansor, Ahmad Fa ...; Mak, Wing Cheung; Khan, Sheroz; visa fler...; Ramli, Noor Amal ...; Pothier, Arnaud; Nordin, Anis Nur ...; visa färre...

Om ämnet

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.