Sökning: onr:"swepub:oai:DiVA.org:liu-18295" >
Methicillin-resista...
Methicillin-resistant Staphylococcus aureus (MRSA) in municipal wastewater : An uncharted threat?
-
- Börjesson, Stefan, 1979- (författare)
- Linköpings universitet,Medicinsk mikrobiologi,Hälsouniversitetet
-
- Matussek, Andreas (författare)
- County Hospital Ryhov, Jönköping, Sweden/Laboratory Services, Unilabs, Göteborg, Sweden
-
- Melin, Sara (författare)
- County Hospital Ryhov, Jönköping, Sweden
-
visa fler...
-
- Löfgren, Sture (författare)
- County Hospital Ryhov, Jönköping, Sweden
-
- Lindgren, Per-Eric (författare)
- Linköpings universitet,Medicinsk mikrobiologi,Hälsouniversitetet
-
visa färre...
-
(creator_code:org_t)
- Engelska.
- Relaterad länk:
-
http://urn.kb.se/res...
-
visa fler...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- Methicillin-resistant S. aureus (MRSA) was recently detected in municipal wastewater, why there is a need for further studies to elucidate if MRSA in wastewater constitutes a health risk, and to determine how wastewater treatment processes affects MRSA. We cultivated MRSA from a full-scale wastewater treatment plant to characterise the indigenous MRSA-flora and to investigate how the wastewater treatment process affects the clonal distribution. MRSA isolates were characterised using spa typing, antibiograms, SSCmec typing and detection of Panton Valentine leukocidin (PVL) genes. We found that the wastewater MRSA-flora has a close genetic relationship to clinical isolates, but we also isolated novel spa types, primarily from the activated sludge treatment step. The number of isolates and the diversity of MRSA are reduced by the treatment process, but the process also selects for more extensive antibiotic resistant strains as well as for PVL positive strains.
Nyckelord
- Staphylococcus aureus
- MRSA
- methicillin
- β-lactam
- SCCmec
- spa typing
- Panton Valentine leukocidin
- PVL
- antibiotic resistance
- antibiogram
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- vet (ämneskategori)
- ovr (ämneskategori)