SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Miehlke Stephan)
 

Search: WFRF:(Miehlke Stephan) > The Process of Deve...

  • Pihl Lesnovska, KatarinaLinköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken (author)

The Process of Developing a Disease Activity Index in Microscopic Colitis

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • 2021-09-25
  • Oxford, United Kingdom :Oxford University Press,2022
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:liu-183268
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-183268URI
  • https://doi.org/10.1093/ecco-jcc/jjab170DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding Agencies: Tillotts Pharma; N-ECCO research grants
  • Background and Aims: Patient-reported outcome measures [PROMs] aim to measure patients perception of how their disorder influences everyday functioning. The objective of this study was to develop a PROM to assess disease activity in microscopic colitis [MC] fulfilling the requirements of the Food and Drug Administration [FDA].Methods: The European Microscopic Colitis Activity Index [E-MCAT] was developed in four steps. [1] A list of symptoms associated with active MC was created by a group of experts in the field. [2] Content validity of the symptoms was performed by experts [n= 14] and patients [n = 79] using the Content Validity Index. [3] Questions and response alternatives were created for each symptom, and validity of the E-MCAI was evaluated with cognitive interviews with patients [n= 7] and by the experts. [4] A pilot postal survey was performed to ensure usability.Results: Seven of the symptoms related to active MC fulfilled the criteria for content validity and were included in the E-MCAI: stool consistency, stool frequency, stools at night, feel a need to pass more stools shortly after a bowel movement, urgent need to empty the bowel, leakage of stool and abdominal pain.The development and validation process resulted in the current version of the E-MCAI consisting of six questions related to MC. Conclusions: The E-MCAI was developed using the methods advocated by the FDA.The evaluation indicates good content validity. Further evaluation will be performed to achieve construct validity, reliability and responsiveness in future cross-sectional and longitudinal studies.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Münch, AndreasLinköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken(Swepub:liu)andsa76 (author)
  • Bonderup, OleRegionhosp Silkeborg, Denmark (author)
  • Magro, FernandoHosp Sao Joao, Portugal (author)
  • Kupcinskas, JuozasLithuanian Univ Hlth Sci, Lithuania; Lithuanian Univ Hlth Sci, Lithuania (author)
  • Zabana, YamileCtr Invest Biomed Red Enfermedades Hepat & Digest, Spain; Univ Barcelona, Spain (author)
  • Tontini, Gian EugenioUniv Milan, Italy; Fdn IRCCS Ca Granda Osped Maggiore Policlin, Italy (author)
  • Munck, Lars KristianZealand Univ Hosp, Denmark; Univ Copenhagen, Denmark (author)
  • Guagnozzi, DanilaCtr Invest Biomed Red Enfermedades Hepat & Digest, Spain; Vall dHebron Res Inst VHIR, Spain (author)
  • Latella, GiovanniUniv Aquila, Italy (author)
  • Fernandez-Banares, FernandoCtr Invest Biomed Red Enfermedades Hepat & Digest, Spain; Univ Barcelona, Spain (author)
  • Miehlke, StephanCtr Digest Dis, Germany; Univ Hosp Eppendorf, Germany (author)
  • Madisch, AhmedCRH Clin Siloah, Germany (author)
  • Wildt, SigneZealand Univ Hosp, Denmark; Univ Copenhagen, Denmark (author)
  • Hjortswang, HenrikLinköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken(Swepub:liu)henhj44 (author)
  • Linköpings universitetAvdelningen för diagnostik och specialistmedicin (creator_code:org_t)

Related titles

  • In:Journal of Crohn's & ColitisOxford, United Kingdom : Oxford University Press16:3, s. 452-4591873-99461876-4479

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view