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Non-invasive estima...
Non-invasive estimation of relative pressure for intracardiac flows using virtual work-energy
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- Marlevi, David (författare)
- Karolinska Institutet,Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, USA
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- Balmus, Maximilian (författare)
- School of Biomedical Engineering and Imaging Sciences, The Rayne Institute, Kings College London, United Kingdom
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- Hessenthaler, Andreas (författare)
- Institute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Germany
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- Viola, Federica (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Fovargue, Daniel (författare)
- School of Biomedical Engineering and Imaging Sciences, The Rayne Institute, Kings College London, United Kingdom
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- Vecchi, Adelaide de (författare)
- School of Biomedical Engineering and Imaging Sciences, The Rayne Institute, Kings College London, United Kingdom
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- Lamata, Pablo (författare)
- School of Biomedical Engineering and Imaging Sciences, The Rayne Institute, Kings College London, United Kingdom
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- Burris, Nicholas S (författare)
- Department of Radiology, University of Michigan, United States of America
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- Pagani, Francis D. (författare)
- Department of Radiology, University of Michigan, United States of America
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- Engvall, Jan, 1953- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV,Region Östergötland, Fysiologiska kliniken US
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- Edelman, Elazer R (författare)
- Institute for Medical Engineering and Science, Massachusetts Institute of Technology, USA
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- Ebbers, Tino, 1972- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Centrum för medicinsk bildvetenskap och visualisering, CMIV
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- Nordsletten, David A (författare)
- School of Biomedical Engineering and Imaging Sciences, The Rayne Institute, Kings College London, SE1 7EH, London, United Kingdom; Department of Surgery and Biomedical Engineering, University of Michigan, 2800 Plymouth Rd, Ann Arbor, MI 48109, United States of America. Electronic address nordslet@umich.com
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(creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: Medical Image Analysis. - : Elsevier. - 1361-8415 .- 1361-8423. ; 68
- Relaterad länk:
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Intracardiac blood flow is driven by differences in relative pressure, and assessing these is critical in understanding cardiac disease. Non-invasive image-based methods exist to assess relative pressure, however, the complex flow and dynamically moving fluid domain of the intracardiac space limits assessment. Recently, we proposed a method, ?WERP, utilizing an auxiliary virtual field to probe relative pressure through complex, and previously inaccessible flow domains. Here we present an extension of ?WERP for intracardiac flow assessments, solving the virtual field over sub-domains to effectively handle the dynamically shifting flow domain. The extended ?WERP is validated in an in-silico benchmark problem, as well as in a patient-specific simulation model of the left heart, proving accurate over ranges of realistic image resolutions and noise levels, as well as superior to alternative approaches. Lastly, the extended ?WERP is applied on clinically acquired 4D Flow MRI data, exhibiting realistic ventricular relative pressure patterns, as well as indicating signs of diastolic dysfunction in an exemplifying patient case. Summarized, the extended ?WERP approach represents a directly applicable implementation for intracardiac flow assessments.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk bildbehandling (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Image Processing (hsv//eng)
Nyckelord
- 4D Flow MRI; Cardiac hemodynamics; Dynamic domains; Fluid mechanics; Relative pressure; Virtual work-energy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Marlevi, David
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Balmus, Maximili ...
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Hessenthaler, An ...
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Viola, Federica
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Fovargue, Daniel
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Vecchi, Adelaide ...
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visa fler...
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Lamata, Pablo
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Burris, Nicholas ...
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Pagani, Francis ...
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Engvall, Jan, 19 ...
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Edelman, Elazer ...
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Ebbers, Tino, 19 ...
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Nordsletten, Dav ...
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- Om ämnet
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- TEKNIK OCH TEKNOLOGIER
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TEKNIK OCH TEKNO ...
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och Medicinteknik
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och Medicinsk bildbe ...
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Medical Image An ...
- Av lärosätet
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Linköpings universitet
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Karolinska Institutet