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Survival after aort...
Survival after aortic root replacement with a stentless xenograft is determined by patient characteristics
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- Dagnegård, H.H. (författare)
- Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
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- Bekke, K. (författare)
- Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
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- Kolseth, S.M. (författare)
- Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
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- Glaser, N. (författare)
- Karolinska Institutet
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- Wallén, C. (författare)
- Linköpings universitet,Institutionen för hälsa, medicin och vård,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- El-Hamamsy, I. (författare)
- Montreal Heart Institute, University of Montreal, Montreal, QC, Canada
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- Vidisson, K.O. (författare)
- Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
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- Lie, A.S. (författare)
- Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
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- Valentin, J.B. (författare)
- Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark
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- Sartipy, U. (författare)
- Karolinska Institutet
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- Haaverstad, R. (författare)
- Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
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- Vanky, Farkas (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland
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- Lefebvre, L. (författare)
- Montreal Heart Institute, University of Montreal, Montreal, QC, Canada
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- Gudbjartsson, T. (författare)
- Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
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- Johnsen, S.P. (författare)
- Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark
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- Søndergaard, L. (författare)
- Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
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- Thyregod, G.H. (författare)
- Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
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- Lund, J.T. (författare)
- Cardio Thoracic Surgical Department, Green Lane Division, Auckland City Hospital, Auckland, New Zealand
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- Ihlemann, N. (författare)
- Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
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- Smerup, M.H. (författare)
- Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
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(creator_code:org_t)
- Mosby Inc.; Elsevier Inc. 2022
- 2022
- Engelska.
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Ingår i: Journal of Thoracic and Cardiovascular Surgery. - : Mosby Inc.; Elsevier Inc.. - 0022-5223 .- 1097-685X. ; 164:6, s. 1712-1724
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http://www.jtcvs.org...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Objectives: Our objective was to examine intermediate-term survival and reinterventions in unselected patients, stratified according to indication, who received a Freestyle (Medtronic Inc, Minneapolis, Minn) bioprosthesis as a full aortic root replacement. Methods: Data from medical records were retrospectively collected for patients who had aortic root replacement using Freestyle bioprostheses between 1999 and 2018 at 6 North-Atlantic centers. Survival status was extracted from national registries and results stratified according to indication for surgery. Results: We included 1030 implantations in 1008 patients with elective indications for surgery: aneurysm (39.8%), small root (8.3%), and other (13.8%), and urgent/emergent indications: endocarditis (26.7%) and Stanford type A aortic dissection (11.4%). Across indications, 46.3% were nonelective cases and 34.0% were reoperations. Median age was 66.0 (interquartile range, 58.0-71.8) years and median follow-up was 5.0 (interquartile range, 2.6-7.9) years. Thirty-day mortality varied from 2.9% to 27.4% depending on indication. Intermediate survival for 90-day survivors with elective indications were not different from the general population standardized for age and sex (P = .95, 83, and .16 for aneurysms, small roots, and other, respectively). In contrast, patients with endocarditis and type A dissection had excess mortality (P < .001). Freedom from valve reinterventions was 95.0% and 94.4% at 5 and 8 years, respectively. In all, 52 patients (5.2%) underwent reinterventions, most because of endocarditis. Conclusions: At intermediate term follow-up this retrospective study provides further support for the use of the Freestyle bioprosthesis in the real-world setting of diverse, complex, and often high-risk aortic root replacement and suggests that outcome is determined by patient and disease, rather than by prosthesis, characteristics. © 2021 The Authors
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- aortic root replacement; endocarditis; full root bioprosthesis; reinterventions; survival; type A dissections
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Dagnegård, H.H.
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Bekke, K.
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Kolseth, S.M.
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Glaser, N.
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Wallén, C.
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El-Hamamsy, I.
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Vidisson, K.O.
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Lie, A.S.
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Valentin, J.B.
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Sartipy, U.
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Haaverstad, R.
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Vanky, Farkas
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Lefebvre, L.
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Gudbjartsson, T.
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Johnsen, S.P.
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Søndergaard, L.
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Thyregod, G.H.
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Lund, J.T.
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Ihlemann, N.
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Smerup, M.H.
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