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Nano toolbox in imm...
Nano toolbox in immune modulation and nanovaccines
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- Azharuddin, Mohammad, 1986- (author)
- Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
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- Zhu, Geyunjian Harry (author)
- Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK
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- Sengupta, Anirban (author)
- Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
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- Hinkula, Jorma, 1958- (author)
- Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten
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- Slater, Nigel K.H. (author)
- Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK
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- Patra, Hirak, 1981- (author)
- Department of Surgical Biotechnology, University College London, London, UK
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(creator_code:org_t)
- Oxford, United Kingdom : Elsevier, 2022
- 2022
- English.
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In: Trends in Biotechnology. - Oxford, United Kingdom : Elsevier. - 0167-7799 .- 1879-3096. ; 40:10, s. 1195-1212
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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Abstract
Subject headings
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- Despite the great success of vaccines over two centuries, the conventional strategy is based on attenuated/altered microorganisms. However, this is not effective for all microbes and often fails to elicit a protective immune response, and sometimes poses unexpected safety risks. The expanding nano toolbox may overcome some of the roadblocks in vaccine development given the plethora of unique nanoparticle (NP)-based platforms that can successfully induce specific immune responses leading to exciting and novel solutions. Nanovaccines necessitate a thorough understanding of the immunostimulatory effect of these nanotools. We present a comprehensive description of strategies in which nanotools have been used to elicit an immune response and provide a perspective on how nanotechnology can lead to future personalized nanovaccines.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- vaccine
- nano toolbox
- nanovaccine
- immune modulation
- immune response
Publication and Content Type
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