Measurement uncertainty for practical use

Coskun, AbdurrahmanEFLM Task & Finish Grp Pract Approach Measurement, Italy; Acibadem Mehmet Ali Aydinlar Univ, Turkey (författare)

Uncertainty is an inseparable part of all kinds of measurements performed in clinical laboratories. Accreditation standards including the ISO/IEC 17025:2017 and ISO 15189:2012 require that laboratories have routines for calculating the measurement uncertainty of reported results. Various guidelines such as CLSI EP29, Nordest 537, and ISO 20914:2019 have proposed methods for this purpose. However, due to the conceived complexity of the proposed calculation methods, these guidelines have not been generally and effectively applied in clinical laboratories. High workload and measurand heterogeneity favor a pragmatic utilitarian approach. The purpose of this paper is to describe such an approach, including its advantages and disadvantages. Measurement uncertainty should include the most influential factors affecting patients test results. Since patients samples for the same measurand can be analyzed in one laboratory or several laboratories using different measuring systems, the measurement uncertainty should be calculated using results obtained from analyzing the same internal quality control material if commutable or patients pooled/split samples.

Theodorsson, ElvarLinköpings universitet,Avdelningen för klinisk kemi och farmakologi,Medicinska fakulteten,Region Östergötland, Klinisk kemi,EFLM Task & Finish Grp Pract Approach Measurement, Italy(Swepub:liu)elvth65 (författare)
Oosterhuis, Wytze P.EFLM Task & Finish Grp Pract Approach Measurement, Italy; Reinier Haga Med Diagnost Ctr, Netherlands (författare)
Sandberg, SverreEFLM Task & Finish Grp Pract Approach Measurement, Italy; Haraldsplass Diaconess Hosp, Norway; Univ Bergen, Norway (författare)
EFLM Task & Finish Grp Pract Approach Measurement, Italy; Acibadem Mehmet Ali Aydinlar Univ, TurkeyAvdelningen för klinisk kemi och farmakologi (creator_code:org_t)

Av författaren/redakt...: Coskun, Abdurrah ...; Theodorsson, Elv ...; Oosterhuis, Wytz ...; Sandberg, Sverre

Om ämnet

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Medicinteknik; och Medicinsk labora ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.