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Dragon 1 Protocol M...
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Korenblik, R.Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands
(author)
Dragon 1 Protocol Manuscript : Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2022-07-05
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Springer,2022
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-187431
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-187431URI
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https://doi.org/10.1007/s00270-022-03176-1DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:150208354URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding Agencies|Dutch Cancer Society (KWF); Abbott Laboratories; Maastricht University; Maastricht University Medical Center; NIHR; Guerbet
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Study Purpose The DRAGON 1 trial aims to assess training, implementation, safety and feasibility of combined portal- and hepatic-vein embolization (PVE/HVE) to accelerate future liver remnant (FLR) hypertrophy in patients with borderline resectable colorectal cancer liver metastases. Methods The DRAGON 1 trial is a worldwide multicenter prospective single arm trial. The primary endpoint is a composite of the safety of PVE/HVE, 90-day mortality, and one year accrual monitoring of each participating center. Secondary endpoints include: feasibility of resection, the used PVE and HVE techniques, FLR-hypertrophy, liver function (subset of centers), overall survival, and disease-free survival. All complications after the PVE/HVE procedure are documented. Liver volumes will be measured at week 1 and if applicable at week 3 and 6 after PVE/HVE and follow-up visits will be held at 1, 3, 6, and 12 months after the resection. Results Not applicable. Conclusion DRAGON 1 is a prospective trial to assess the safety and feasibility of PVE/HVE. Participating study centers will be trained, and procedures standardized using Work Instructions (WI) to prepare for the DRAGON 2 randomized controlled trial. Outcomes should reveal the accrual potential of centers, safety profile of combined PVE/HVE and the effect of FLR-hypertrophy induction by PVE/HVE in patients with CRLM and a small FLR.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Olij, B.Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands
(author)
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Aldrighetti, L. A.Osped San Raffaele, Italy
(author)
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Abu Hilal, M.Fdn Poliambulanza, Italy,Oxford Univ Hosp NHS, England,Univ Hosp Heidelberg, Germany,Queen Elizabeth Hosp Birmingham NHS, England,Erasmus MC, Netherlands,Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany
(author)
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Ahle, Margareta,1966-Region Östergötland, Röntgenkliniken i Linköping(Swepub:liu)marah33
(author)
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Arslan, B.Rush Univ Med Ctr, IL USA,Cantonal Hosp Winterthur, Switzerland
(author)
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van Baardewijk, L. J.Maxima Med Ctr, Netherlands,Hop Erasme, Belgium
(author)
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Baclija, IClin Favoriten, Austria
(author)
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Bent, C.Royal Bournemouth & Christchurch Hosp, England; Royal Bournemouth & Christchurch Hosp, England,Aintree Univ Hosp NHS Fdn Trust, England
(author)
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Bertrand, C. L.CHU UCLouvain Namur, Belgium
(author)
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Björnsson, Bergthor,1975-Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)berbj34
(author)
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de Boer, M. T.Univ Med Ctr Groningen, Netherlands
(author)
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de Boer, S. W.Maastricht Univ Med Ctr, Netherlands
(author)
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Bokkers, R. P. H.Univ Med Ctr Groningen, Netherlands,Kings Coll Hosp NHS, England
(author)
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Rinkes, I. H. M. BorelUniv Med Ctr Utrecht, Netherlands,St Clara Spital, Switzerland,Gemelli Univ Hosp, Italy,Amsterdam Univ Med Ctr Locat VU, Netherlands
(author)
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Breitenstein, S.Cantonal Hosp Winterthur, Switzerland
(author)
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Bruijnen, R. C. G.Univ Med Ctr Utrecht, Netherlands,Royal Prince Alfred Hosp, Australia
(author)
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Bruners, P.Univ Hosp Aachen, Germany
(author)
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Camacho, J. C.Mem Sloan Kettering Canc Ctr, NY 10021 USA,Western Hlth Footscray, Australia,Univ Hosp Bonn, Germany,Rush Univ Med Ctr, IL USA
(author)
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Cappelli, A.St Orsola Malpighi Hosp, Italy
(author)
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Carling, U.Univ Hosp Oslo, Norway
(author)
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Chan, B. K. Y.Aintree Univ Hosp NHS Fdn Trust, England
(author)
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Chang, D. H.Univ Hosp Heidelberg, Germany,Univ Hosp Aachen, Germany
(author)
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Choi, J.Western Hlth Footscray, Australia
(author)
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Codina Font, J.Univ Hosp Dr Josep Trueta Girona, Spain
(author)
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Crawford, M.Royal Prince Alfred Hosp, Australia,Yale Sch Med, CT USA,Univ Hosp Bonn, Germany
(author)
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Croagh, D.Monash Hlth, Australia,Maastricht Univ Med Ctr, Netherlands
(author)
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Cugat, E.Univ Hosp Germans Trias I Pujol, Spain
(author)
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Davis, R.Aintree Univ Hosp NHS Fdn Trust, England,Royal Free Hosp NHS, England
(author)
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De Boo, D. W.Monash Hlth, Australia
(author)
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De Cobelli, F.Osped San Raffaele, Italy,Hosp Clin Barcelona, Spain
(author)
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De Wispelaere, J. F.CHU UCLouvain Namur, Belgium
(author)
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van Delden, O. M.Karolinska Institutet,Amsterdam Univ Med Ctr Locat AMC, Netherlands,Karolinska Univ Hosp, Sweden
(author)
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Delle, M.Karolinska Univ Hosp, Sweden
(author)
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Detry, O.CHU Liege, Belgium
(author)
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Dili, A.CHU UCLouvain Namur, Belgium
(author)
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Erdmann, J. IAmsterdam Univ Med Ctr Locat AMC, Netherlands,Osped Maggiore Bologna, Italy
(author)
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Fisher, O.Royal Prince Alfred Hosp, Australia
(author)
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Fondevila, C.Hosp Clin Barcelona, Spain
(author)
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Fretland, A.Univ Hosp Oslo, Norway
(author)
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Garcia Borobia, F.Hosp Parc Tauli Sabadell, Spain
(author)
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Gelabert, A.Hosp Parc Tauli Sabadell, Spain; Univ Hosp Mutua Terassa, Spain,Klinikum Saarbrucken gGmbH, Germany
(author)
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Gerard, L.CHU Liege, Belgium,Maxima Med Ctr, Netherlands
(author)
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Giuliante, F.Gemelli Univ Hosp Rome, Italy,Clarunis Univ Hosp, Switzerland
(author)
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Gobardhan, P. D.Amphia, Netherlands
(author)
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Gomez, F.Hosp Clin Barcelona, Spain
(author)
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Grunberger, T.Clin Favoriten, Austria
(author)
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Grunhagen, D. J.Erasmus MC, Netherlands
(author)
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Guitart, J.Univ Hosp Mutua Terassa, Spain
(author)
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Hagendoorn, J.Univ Med Ctr Utrecht, Netherlands
(author)
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Heil, J.Univ Hosp Frankfurt, Germany
(author)
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Heise, D.Univ Hosp Aachen, Germany
(author)
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Herrero, E.Univ Hosp Mutua Terassa, Spain
(author)
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Hess, G. F.Clarunis Univ Hosp, Switzerland
(author)
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Hoffmann, M. H.St Clara Spital, Switzerland
(author)
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Iezzi, R.Gemelli Univ Hosp, Italy
(author)
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Imani, F.Amphia, Netherlands
(author)
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Nguyen, J.Western Hlth Footscray, Australia,Univ Hosp Southampton NHS, England
(author)
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Jovine, E.Osped Maggiore Bologna, Italy
(author)
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Kalff, J. C.Univ Hosp Bonn, Germany
(author)
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Kazemier, G.Amsterdam Univ Med Ctr Locat VU, Netherlands
(author)
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Kingham, T. P.Mem Sloan Kettering Canc Ctr, NY 10021 USA
(author)
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Kleeff, J.Univ Hosp Halle Saale, Germany
(author)
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Kollmar, O.Clarunis Univ Hosp, Switzerland
(author)
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Leclercq, W. K. G.Maxima Med Ctr, Netherlands
(author)
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Lopez Ben, S.Univ Hosp Dr Josep Truetade Girona, Spain,Univ Hosp Miguel Servet, Spain
(author)
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Lucidi, VHop Erasme, Belgium
(author)
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MacDonald, A.Oxford Univ Hosp NHS, England
(author)
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Madoff, D. C.Yale Sch Med, CT USA
(author)
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Manekeller, S.Univ Hosp Bonn, Germany,IRCCS Azienda Osped Univ Bologna, Italy,Univ Med Ctr Utrecht, Netherlands
(author)
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Martel, G.Ottawa Hosp, Canada
(author)
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Mehrabi, A.Univ Hosp Heidelberg, Germany
(author)
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Mehrzad, H.Queen Elizabeth Hosp Birmingham NHS, England
(author)
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Meijerink, M. R.Amsterdam Univ Med Ctr Locat VU, Netherlands,Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany
(author)
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Menon, K.Kings Coll Hosp NHS, England
(author)
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Metrakos, P.McGill Univ Hlth Ctr, Canada
(author)
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Meyer, C.Univ Hosp Bonn, Germany
(author)
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Moelker, A.Erasmus MC, Netherlands
(author)
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Modi, S.Univ Hosp Southampton NHS, England
(author)
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Montanari, N.Osped Maggiore Bologna, Italy
(author)
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Navines, J.Univ Hosp Germans Trias I Pujol, Spain
(author)
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Neumann, U. P.Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany
(author)
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Peddu, P.Kings Coll Hosp NHS, England,Queen Elizabeth Hosp Birmingham NHS, England
(author)
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Primrose, J. N.Univ Hosp Southampton NHS, England
(author)
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Qu, X.Fundan Univ, Peoples R China
(author)
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Raptis, D.Royal Free Hosp NHS, England
(author)
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Ratti, F.Osped San Raffaele, Italy
(author)
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Ridouani, F.Mem Sloan Kettering Canc Ctr, NY 10021 USA
(author)
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Rogan, C.Royal Prince Alfred Hosp, Australia
(author)
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Ronellenfitsch, U.Univ Hosp Halle Saale, Germany
(author)
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Ryan, S.Ottawa Hosp, Canada
(author)
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Sallemi, C.Fdn Poliambulanza, Italy
(author)
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Sampere Moragues, J.Univ Hosp Germans Trias I Pujol, Spain
(author)
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Sandström, Per A,1965-Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)persa07
(author)
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Sarria, L.Univ Hosp Miguel Servet, Spain
(author)
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Schnitzbauer, A.Univ Hosp Frankfurt, Germany,Newcastle Upon Tyne Hosp NHS, England
(author)
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Serenari, M.IRCCS Azienda Osped Univ Bologna, Italy
(author)
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Serrablo, A.Univ Hosp Miguel Servet, Spain
(author)
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Smits, M. L. J.Univ Med Ctr Utrecht, Netherlands
(author)
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Sparrelid, E.Karolinska Institutet,Karolinska Univ Hosp, Sweden
(author)
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Spuntrup, E.Klinikum Saarbrucken gGmbH, Germany
(author)
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Stavrou, G. A.Klinikum Saarbrucken gGmbH, Germany
(author)
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Sutcliffe, R. P.Queen Elizabeth Hosp Birmingham NHS, England
(author)
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Tancredi, IHop Erasme, Belgium
(author)
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Tasse, J. C.Rush Univ Med Ctr, IL USA
(author)
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Udupa, VOxford Univ Hosp NHS, England
(author)
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Valenti, D.McGill Univ Hlth Ctr, Canada
(author)
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Fundora, Y.Hosp Clin Barcelona, Spain
(author)
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Vogl, T. J.Univ Hosp Frankfurt, Germany
(author)
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Wang, X.Fundan Univ, Peoples R China
(author)
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White, S. A.Newcastle Upon Tyne Hosp NHS, England
(author)
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Wohlgemuth, W. A.Univ Hosp Halle Saale, Germany
(author)
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Yu, D.Royal Free Hosp NHS, England
(author)
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Zijlstra, I. A. J.Amsterdam Univ Med Ctr Locat VU, Netherlands
(author)
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Binkert, C. A.Cantonal Hosp Winterthur, Switzerland
(author)
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Bemelmans, M. H. A.Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany
(author)
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van der Leij, C.Maastricht Univ Med Ctr, Netherlands
(author)
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Schadde, E.Cantonal Hosp Winterthur, Switzerland; Rush Univ Med Ctr Chicago, IL USA
(author)
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van Dam, R. M.Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, Netherlands; Univ Hosp Aachen, Germany
(author)
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Maastricht Univ, Netherlands; Maastricht Univ Med Ctr, NetherlandsOsped San Raffaele, Italy
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In:Cardiovascular and Interventional Radiology: Springer45, s. 1391-13980174-15511432-086X
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Korenblik, R.
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Aldrighetti, L. ...
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Abu Hilal, M.
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Ahle, Margareta, ...
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Arslan, B.
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Choi, J.
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Gelabert, A.
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Grunhagen, D. J.
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Guitart, J.
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Hagendoorn, J.
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Heil, J.
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Heise, D.
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Herrero, E.
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Hess, G. F.
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Hoffmann, M. H.
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Iezzi, R.
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Imani, F.
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Nguyen, J.
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Jovine, E.
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Kalff, J. C.
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Kazemier, G.
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Kingham, T. P.
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Kleeff, J.
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Kollmar, O.
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Leclercq, W. K. ...
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Lopez Ben, S.
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Lucidi, V
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MacDonald, A.
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Madoff, D. C.
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Manekeller, S.
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Martel, G.
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Mehrabi, A.
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Mehrzad, H.
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Meijerink, M. R.
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Menon, K.
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Metrakos, P.
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Meyer, C.
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Moelker, A.
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Modi, S.
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Montanari, N.
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Navines, J.
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Neumann, U. P.
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Peddu, P.
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Primrose, J. N.
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Qu, X.
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Raptis, D.
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Ratti, F.
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Ronellenfitsch, ...
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Sallemi, C.
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Sampere Moragues ...
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Sandström, Per A ...
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Sarria, L.
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Schnitzbauer, A.
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Serenari, M.
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Serrablo, A.
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Smits, M. L. J.
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Sparrelid, E.
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Spuntrup, E.
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Stavrou, G. A.
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Sutcliffe, R. P.
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Tancredi, I
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Tasse, J. C.
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Udupa, V
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Valenti, D.
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Fundora, Y.
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Vogl, T. J.
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Schadde, E.
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