Outer hair cell driven reticular lamina mechanical distortion in living cochleae

Cochlear distortions afford researchers and clinicians a glimpse into the conditions and properties of inner ear signal processing mechanisms. Until recently, our examination of these distortions has been limited to measuring the vibration of the basilar membrane or recording acoustic distortion output in the ear canal. Despite its importance, the generation mechanism of cochlear distortion remains a substantial task to understand. The ability to measure the vibration of the reticular lamina in rodent models is a recent experimental advance. Surprising mechanical properties have been revealed. These properties merit both discussion in context with our current understanding of distortion, and appraisal of the significance of new interpretations of cochlear mechanics. This review focusses on some of the recent data from our research groups and discusses the implications of these data on our understanding of vocalization processing in the periphery, and their influence upon future experimental directions. (C) 2021 Elsevier B.V. All rights reserved.

He, W. X.Oregon Hlth & Sci Univ, OR 97239 USA (author)
Fridberger, AndersLinköpings universitet,Avdelningen för neurobiologi,Medicinska fakulteten(Swepub:liu)andfr39 (author)
Ren, T. Y.Department of Otolaryngology, Head and Neck Surgery, Oregon Health & Science University, Portland OR, United States (author)
Nuttall, A. L.Oregon Hlth & Sci Univ, OR 97239 USA (author)
Oregon Hlth & Sci Univ, OR 97239 USAAvdelningen för neurobiologi (creator_code:org_t)

By the author/editor: Burwood, G.; He, W. X.; Fridberger, Ande ...; Ren, T. Y.; Nuttall, A. L.

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Otorhinolaryngol ...

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