Lifestyle and dietary determinants of serum apolipoprotein A1 and apolipoprotein B concentrations : Cross-sectional analyses within a Swedish Cohort of 24,984 individuals

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Frondelius, KasperLund University (författare)

Lifestyle and dietary determinants of serum apolipoprotein A1 and apolipoprotein B concentrations : Cross-sectional analyses within a Swedish Cohort of 24,984 individuals

Artikel/kapitelEngelska2017

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2017-02-28
MDPI AG,2017

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LIBRIS-ID:oai:lup.lub.lu.se:b9c4d77e-ad13-4011-83aa-ca4a636e4717
https://lup.lub.lu.se/record/b9c4d77e-ad13-4011-83aa-ca4a636e4717URI
https://doi.org/10.3390/nu9030211DOI

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Språk:engelska
Sammanfattning på:engelska

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Low serum apolipoprotein (Apo) A1 concentrations and high serum ApoB concentrations may be better markers of the risk of cardiovascular disease than high-density lipoprotein (HDL) and low-density lipoprotein (LDL). However, the associations between modifiable lifestyle factors and Apo concentrations have not been investigated in detail. Therefore, this study investigated the associations between Apo concentrations and education, lifestyle factors and dietary intake (macronutrients and 34 food groups). These cross-sectional associations were examined among 24,984 individuals in a Swedish population-based cohort. Baseline examinations of the cohort were conducted between 1991 and 1996. Dietary intake was assessed using a modified diet history method. The main determinants of high ApoA1 concentrations (r between 0.05 and 0.25) were high alcohol consumption, high physical activity, non-smoking, and a low body mass index (BMI), and the main determinants of high ApoB concentrations were smoking and a high BMI. The intake of sucrose and food products containing added sugar (such as pastries, sweets, chocolate, jam/sugar and sugar-sweetened beverages) was negatively correlated with ApoA1 concentrations and positively correlated with ApoB concentrations and the ApoB/ApoA1 ratio, whereas the intake of fermented dairy products, such as fermented milk and cheese, was positively correlated with ApoA1 concentrations and negatively correlated with the ApoB/ApoA1 ratio. These results indicate that smoking, obesity, low physical activity, low alcohol consumption and a diet high in sugar and low in fermented dairy products are correlated with an unfavorable Apo profile.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Näringslära hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Nutrition and Dietetics hsv//eng
Apolipoproteins
Diet
Epidemiology
Nutrition

Biuppslag (personer, institutioner, konferenser, titlar ...)

Borg, MadeleneLund University (författare)
Ericson, UlrikaLund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups(Swepub:lu)medf-upe (författare)
Borné, YanLund University,Lunds universitet,Kardiovaskulär forskning - epidemiologi,Forskargrupper vid Lunds universitet,Cardiovascular Research - Epidemiology,Lund University Research Groups(Swepub:lu)med-boy (författare)
Melander, OlleLund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups(Swepub:lu)endo-ome (författare)
Sonestedt, EmilyLund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups(Swepub:lu)medf-eso (författare)
Lund UniversityDiabetes - kardiovaskulär sjukdom (creator_code:org_t)

Sammanhörande titlar

Ingår i:Nutrients: MDPI AG9:32072-6643

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Av författaren/redakt...: Frondelius, Kasp ...; Borg, Madelene; Ericson, Ulrika; Borné, Yan; Melander, Olle; Sonestedt, Emily

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Näringslära

Artiklar i publikationen: Nutrients

Av lärosätet: Lunds universitet

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