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Considering sex as a biological variable in preclinical research

Miller, Leah R. (författare)
Office of Research on Women's Health, Bethesda, Maryland, USA
Marks, Cheryl (författare)
Division of Cancer BiologyNational Cancer Institute Bethesda Maryland USA,Division of Cancer Biology, National Cancer Institute, Bethesda, Maryland, USA
Becker, Jill B. (författare)
Molecular and Behavioral Neuroscience Institute, Ann Arbor, Michigan, USA
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Hurn, Patricia D. (författare)
School of NursingUniversity of Michigan Ann Arbor Michigan USA,School of Nursing, University of Michigan, Ann Arbor, Michigan, USA
Chen, Wei‐Jung (författare)
Department of Neuroscience and Experimental TherapeuticsTexas A&M Health Science Center Bryan Texas USA,Department of Neuroscience and Experimental Therapeutics, Texas A&M Health Science Center, Bryan, Texas, USA
Woodruff, Teresa (författare)
Women's Health Research InstituteNorthwestern University Chicago Illinois USA,Women's Health Research Institute, Northwestern University, Chicago, Illinois, USA
McCarthy, Margaret M. (författare)
Department of PharmacologyUniversity of Maryland Baltimore Maryland USA,Department of Pharmacology, University of Maryland, Baltimore, Maryland, USA,Department of Surgery and Physiology Rochester Minnesota USA;Department of Biomedical EngineeringMayo Clinic Rochester Minnesota USA
Sohrabji, Farida (författare)
Department of Neuroscience and Experimental TherapeuticsTexas A&M Health Science Center Bryan Texas USA,Department of Neuroscience and Experimental Therapeutics, Texas A&M Health Science Center, Bryan, Texas, USA
Schiebinger, Londa (författare)
History of ScienceStanford University Stanford California USA,History of Science, Stanford University, Stanford, California, USA
Wetherington, Cora Lee (författare)
National Institute on Drug AbuseNational Institutes of Health Bethesda Maryland USA,National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland, USA
Makris, Susan (författare)
Office of Research and DevelopmentNational Center for Environmental Assessment, U.S. Environmental Protection Agency Washington D.C. USA,Office of Research and Development, National Center for Environmental Assessment, U.S. Environmental Protection Agency, Washington, D.C., USA
Arnold, Arthur P. (författare)
Department of Integrative Biology and Physiology California USA;Laboratory of Neuroendocrinology of the Brain Research InstituteUniversity of California, Los Angeles, Los Angeles California USA,Department of Integrative Biology and Physiology, California, USA; Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles, Los Angeles, California, USA
Einstein, Gillian, 1952- (författare)
Department of Psychology Toronto Ontario Canada;The Dalla Lana School of Public HealthUniversity of Toronto Toronto Ontario Canada;Women's College Research Institute Toronto Ontario Canada,Department of Psychology, Toronto, Ontario, Canada; The Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Women's College Research Institute, Toronto, Ontario, Canada
Miller, Virginia M. (författare)
Department of Surgery and Physiology Rochester Minnesota USA;Department of Biomedical EngineeringMayo Clinic Rochester Minnesota USA,Department of Surgery and Physiology, Rochester, Minnesota, USA; Department of Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, USA
Sandberg, Kathryn (författare)
Department of Medicine Washington D.C. USA;Center for the Study of Sex Differences in HealthAging and Disease, Georgetown University Medical Center Washington D.C. USA,Department of Medicine, Washington, D.C., USA; Center for the Study of Sex Differences in Health, Aging and Disease, Georgetown University Medical Center, Washington, D.C., USA
Maier, Susan (författare)
Office of Research on Women's Health, Bethesda, Maryland, USA
Cornelison, Terri L. (författare)
Office of Research on Women's Health, Bethesda, Maryland, USA
Clayton, Janine A. (författare)
Office of Research on Women's Health, Bethesda, Maryland, USA
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 (creator_code:org_t)
2016-09-28
2016
Engelska.
Ingår i: The FASEB Journal. - : Wiley. - 0892-6638 .- 1530-6860. ; 31:1, s. 29-34
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • In June 2015, the National Institutes of Health (NIH) released a Guide notice (NOT-OD-15-102) that highlighted the expectation of the NIH that the possible role of sex as a biologic variable be factored into research design, analyses, and reporting of vertebrate animal and human studies. Anticipating these guidelines, the NIH Office of Research on Women's Health, in October 2014, convened key stakeholders to discuss methods and techniques for integrating sex as a biologic variable in preclinical research. The workshop focused on practical methods, experimental design, and approaches to statistical analyses in the use of both male and female animals, cells, and tissues in preclinical research. Workshop participants also considered gender as a modifier of biology. This article builds on the workshop and is meant as a guide to preclinical investigators as they consider methods and techniques for inclusion of both sexes in preclinical research and is not intended to prescribe exhaustive/specific approaches for compliance with the new NIH policy.-Miller, L. R., Marks, C., Becker, J. B., Hurn, P. D., Chen, W.-J., Woodruff, T., McCarthy, M. M., Sohrabji, F., Schiebinger, L., Wetherington, C. L., Makris, S., Arnold, A. P., Einstein, G., Miller, V. M., Sandberg, K., Maier, S., Cornelison, T. L., Clayton, J. A. Considering sex as a biological variable in preclinical research.

Ämnesord

SAMHÄLLSVETENSKAP  -- Annan samhällsvetenskap -- Genusstudier (hsv//swe)
SOCIAL SCIENCES  -- Other Social Sciences -- Gender Studies (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)
SOCIAL SCIENCES  -- Psychology (hsv//eng)

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