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The medicinal chemi...
The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity
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- Semwal, Prabhakar (författare)
- Grap Era Deemed Univ, India
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- Rauf, Abdur (författare)
- Univ Swabi, Pakistan
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- Olatunde, Ahmed (författare)
- Abubakar Tafawa Balewa Univ, Nigeria
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- Singh, Pooja (författare)
- Grap Era Deemed Univ, India
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- Zaky Khalifa, Mohamed Yassin Zaky (författare)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Onkologiska kliniken US,Beni Suef Univ, Egypt
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- Islam, Md. Mozahidul (författare)
- Independent Univ, Bangladesh
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- Khalil, Anees Ahmed (författare)
- Univ Lahore, Pakistan
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- Aljohani, Abdullah S. M. (författare)
- Qassim Univ, Saudi Arabia
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- Al Abdulmonem, Waleed (författare)
- Qassim Univ, Saudi Arabia
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- Ribaudo, Giovanni (författare)
- Univ Brescia, Italy
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(creator_code:org_t)
- SPRINGERNATURE, 2023
- 2023
- Engelska.
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Ingår i: NATURAL PRODUCTS AND BIOPROSPECTING. - : SPRINGERNATURE. - 2192-2195. ; 13:1
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Urtica dioica is a perennial herb from the family of Urticaceae that is commonly known as stinging nettle. This plant is widespread in Europe, Africa, America, and a part of Asia, as it adapts to different environments and climatic conditions. The leaves, stalk, and bark of U. dioica found applications in the field of nutrition, cosmetics, textile, pest control and pharmacology. In this connection, bioactive chemical constituents such as flavonoids, phenolic acids, amino acids, carotenoids, and fatty acids have been isolated from the plant. With this review, we aim at providing an updated and comprehensive overview of the contributions in literature reporting computational, in vitro, pre-clinical and clinical data supporting the therapeutic applications of U. dioica. Experimental evidence shows that U. dioica constituents and extracts can provide neuroprotective effects by acting through a combination of different molecular mechanisms, that are discussed in the review. These findings could lay the basis for the identification and design of more effective tools against neurodegenerative diseases.
Ämnesord
- LANTBRUKSVETENSKAPER -- Bioteknologi med applikationer på växter och djur -- Växtbioteknologi (hsv//swe)
- AGRICULTURAL SCIENCES -- Agricultural Biotechnology -- Plant Biotechnology (hsv//eng)
Nyckelord
- Urtica dioica; Neuroprotection; Natural compounds; Flavonoids; Medicinal chemistry
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Semwal, Prabhaka ...
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Rauf, Abdur
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Olatunde, Ahmed
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Singh, Pooja
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Zaky Khalifa, Mo ...
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Islam, Md. Mozah ...
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Khalil, Anees Ah ...
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Aljohani, Abdull ...
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Al Abdulmonem, W ...
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Ribaudo, Giovann ...
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LANTBRUKSVETENSK ...
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och Bioteknologi med ...
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och Växtbioteknologi
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Linköpings universitet