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  • Choi, SungchulYonsei Univ, South Korea (författare)

Global burden of primary liver cancer and its asso- ciation with underlying aetiologies, sociodemo- graphic status, and sex differences from 1990-2019: A DALY-based analysis of the Global Burden of Disease 2019 study

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • 2023-01-04
  • KOREAN ASSOC STUDY LIVER,2023
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:liu-194822
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-194822URI
  • https://doi.org/10.3350/cmh.2022.0316DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:152763758URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies|National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [2019R1A2C4070136]; Technology Innovation Program - Ministry of Trade, Industry & Energy (MOTIE, Korea) [20013712]; National Research Foundation of Korea [NRF-2021 R1I1A2059735]
  • Background/Aims: Global distribution of dominant liver cancer aetiologies has significantly changed over the past decades. This study analyzed the updated temporal trends of liver cancer aetiologies and sociodemographic status in 204 countries and territories from 1990 to 2019.Methods: The Global Burden of Disease 2019 report was used for statistical analysis. In addition, we performed stratification analysis to five quintiles using sociodemographic index and 21 geographic regions.Results: The crude numbers of liver cancer disease-adjusted life years (DALYs) and deaths significantly increased during the study period (DALYs; 11,278,630 in 1990 and 12,528,422 in 2019, deaths; 365,215 in 1990 and 484,577 in 2019). However, the Age-standardized DALY and mortality rates decreased. Hepatitis B virus (HBV) remains the leading cause of liver cancer DALYs and mortality, followed by hepatitis C virus (HCV), alcohol consumption, and non-alcoholic steatohepatitis/non-alcoholic fatty liver disease (NASH/NAFLD). Although Age-standardized DALY and mortality rates of liver cancer due to HBV and HCV have decreased, the rates due to alcohol consumption and NASH/NAFLD have increased. In 2019, the population of the East Asia region had the highest Age-standardized DALY and mortality rates, followed by high-income Asia-Pacific and Central Asia populations. Although East Asia and high-income Asia-Pacific regions showed a decrease during the study period, Age-standardized DALY rates increased in Central Asia. High-income North American and Australasian populations also showed a significant increase in Age-standardized DALY.Conclusions: Liver cancer remains an ongoing global threat. The burden of liver cancer associated with alcohol consumption and NASH/NAFLD is markedly increasing and projected to continuously increase. (Clin Mol Hepatol 2023;29:433-452)

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Kim, Beom KyungYonsei Univ, South Korea; Yonsei Univ, South Korea; Yonsei Univ Hlth Syst, South Korea (författare)
  • Yon, Dong KeonKyung Hee Univ, South Korea (författare)
  • Lee, Seung WonSungkyunkwan Univ, South Korea (författare)
  • Lee, Han GyeolYonsei Univ, South Korea (författare)
  • Chang, Ho HyeokYonsei Univ, South Korea (författare)
  • Park, SeoyeonYonsei Univ, South Korea (författare)
  • Koyanagi, AiCIBERSAM, Spain; Pg Lluis Co 23, Spain (författare)
  • Jacob, LouisCIBERSAM, Spain; Univ Paris Cite, France (författare)
  • Dragioti, ElenaLinköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Smärt och rehabiliteringscentrum(Swepub:liu)eledr71 (författare)
  • Radua, JoaquimUniv Barcelona, Spain; Karolinska Inst, Sweden; Kings Coll London, England (författare)
  • Shin, Jae IlYonsei Univ, South Korea (författare)
  • Kim, Seung UpYonsei Univ, South Korea; Yonsei Univ, South Korea; Yonsei Univ Hlth Syst, South Korea (författare)
  • Smith, LeeAnglia Ruskin Univ, England (författare)
  • Yonsei Univ, South KoreaYonsei Univ, South Korea; Yonsei Univ, South Korea; Yonsei Univ Hlth Syst, South Korea (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Clinical and Molecular Hepatology: KOREAN ASSOC STUDY LIVER29:2, s. 433-4522287-27282287-285X

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