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  • Solmi, MarcoUniv Ottawa, Canada; Ottawa Hosp, Canada; Univ Ottawa, Canada; Univ Ottawa, Canada; Univ Southampton, England; Charite Univ Med Berlin, Germany (författare)

Incidence, prevalence, and global burden of schizophrenia-data, with critical appraisal, from the Global Burden of Disease (GBD) 2019

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • SPRINGERNATURE,2023
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:liu-196632
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-196632URI
  • https://doi.org/10.1038/s41380-023-02138-4DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenias burden and epidemiological estimates in some countries have been published, but updated estimates of prevalence, incidence, and schizophrenia-related disability at the global level are lacking. Here, we present the data from and critically discuss the Global Burden of Diseases, Injuries, and Risk Factors Study data, focusing on temporal changes in schizophrenias prevalence, incidence, and disability-adjusted life years (DALYs) globally. From 1990 to 2019, schizophrenia raw prevalence (14.2 to 23.6 million), incidence (941,000 to 1.3 million), and DALYs (9.1 to 15.1 million) increased by over 65%, 37%, and 65% respectively, while age-standardized estimates remained stable globally. In countries with high socio-demographic index (SDI), both prevalence and DALYs increased, while in those with low SDI, the age-standardized incidence decreased and DALYs remained stable. The male/female ratio of burden of schizophrenia has remained stable in the overall population over the past 30 years (i.e., M/F = 1.1), yet decreasing from younger to older age groups (raw prevalence in females higher than males after age 65, with males having earlier age of onset, and females longer life expectancy). Results of this work suggest that schizophrenias raw prevalence, incidence, and burden have been increasing since 1990. Age-adjusted estimates did not reduce. Schizophrenia detection in low SDI countries is suboptimal, and its prevention/treatment in high SDI countries should be improved, considering its increasing prevalence. Schizophrenia sex ratio inverts throughout the lifespan, suggesting different age of onset and survival by sex. However, prevalence and burden estimates for schizophrenia are probably underestimated. GBD does not account for mortality from schizophrenia (and other mental disorders, apart from anorexia nervosa).

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Seitidis, GeorgiosUniv Ioannina, Greece (författare)
  • Mavridis, DimitrisUniv Ioannina, Greece; Paris Descartes Univ, France (författare)
  • Correll, Christoph U. U.Charite Univ Med Berlin, Germany; Zucker Hillside Hosp, NY USA; Donald & Barbara Zucker Sch Med Hofstra Northwell, NY USA; Feinstein Inst Med Res, NY USA (författare)
  • Dragioti, ElenaLinköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Region Östergötland, Smärt och rehabiliteringscentrum(Swepub:liu)eledr71 (författare)
  • Guimond, SynthiaUniv Quebec Outaouais, Canada; Univ Ottawa, Canada (författare)
  • Tuominen, LauriUniv Ottawa, Canada; Univ Ottawa, Canada (författare)
  • Dargel, AroldoUniv Ottawa, Canada; Ottawa Hosp, Canada; Univ Ottawa, Canada; Univ Ottawa, Canada (författare)
  • Carvalho, Andre F. F.Deakin Univ, Australia (författare)
  • Fornaro, MicheleFederico II Univ Naples, Italy (författare)
  • Maes, MichaelUniv Elect Sci & Technol China, Peoples R China; Chulalongkorn Univ, Thailand; King Chulalongkorn Mem Hosp, Thailand; Med Univ Plovdiv, Bulgaria; Med Univ Plovdiv, Bulgaria (författare)
  • Monaco, FrancescoASL Salerno, Italy; European Biomed Res Inst Salerno EBRIS, Italy (författare)
  • Song, MinjinYonsei Univ, South Korea (författare)
  • Shin, Jae IlYonsei Univ, South Korea (författare)
  • Cortese, SamueleUniv Southampton, England; Univ Southampton, England; NYU, NY USA; Solent NHS Trust, England (författare)
  • Univ Ottawa, Canada; Ottawa Hosp, Canada; Univ Ottawa, Canada; Univ Ottawa, Canada; Univ Southampton, England; Charite Univ Med Berlin, GermanyUniv Ioannina, Greece (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Molecular Psychiatry: SPRINGERNATURE28:53191359-41841476-5578

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