Pan-European survey on current treatment strategies in patients with upfront resectable colorectal liver metastases

Kuiper, Babette I.Vrije Univ Amsterdam, Netherlands; Canc Ctr Amsterdam, Netherlands (author)

Background: There is a lack of consensus on the definition of upfront resectability and use of perioperative systemic therapy for colorectal liver metastases (CRLM). This survey aimed to summarize the current treatment strategies for upfront resectable CRLM throughout Europe. Methods: A survey was sent to all members of the European-African Hepato-Pancreato-Biliary Association to gain insight into the current views on resectability and the use of systemic therapy for upfront Results: The survey was completed by 87 surgeons from 24 countries. The resectability of CRLM is mostly based on the volume of the future liver remnant, while considering tumor biology. Thermal ablation was considered as an acceptable adjunct to resection in parenchymal-sparing CRLM surgery by 77 % of the respondents. A total of 40.2 % of the respondents preferred standard perioperative systemic Conclusion: Among the participating European hepato-pancreato-biliary surgeons, there is a high degree of consensus on the definition of CRLM resectability. However, there is much variety in the use of adjunctive thermal ablation. Major variations persist in the use of perioperative systemic therapy in cases of upfront resectable CRLM, stressing the need for further evidence and a consensus.

Abu Hilal, MohammadPoliambulanza Fdn Hosp, Italy (author)
Aldrighetti, Luca A.IRCCS San Raffaele Hosp, Italy (author)
Björnsson, BergthorLinköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Kirurgiska kliniken US(Swepub:liu)berbj34 (author)
D'hondt, MathieuGroeninge Hosp, Belgium (author)
Dopazo, CristinaUniv Autonoma Barcelona, Spain (author)
Fretland, Asmund A.Univ Oslo, Norway; Univ Oslo, Norway (author)
Isoniemi, HelenaHelsinki Univ Hosp, Finland; Univ Helsinki, Finland (author)
Jonas, J. PhilipUniv Hosp Zurich, Switzerland (author)
Kazemier, GeertVrije Univ Amsterdam, Netherlands; Canc Ctr Amsterdam, Netherlands (author)
Lesurtel, MickaelHop Beaujon, France (author)
Primrose, JohnUniv Hosp Southampton, England (author)
Schnitzbauer, Andreas A.Univ Hosp Frankfurt, Germany (author)
Buffart, TinekeCanc Ctr Amsterdam, Netherlands; Vrije Univ Amsterdam, Netherlands (author)
Gruenberger, BirgitWr Neustadt Hosp, Austria (author)
Swijnenburg, Rutger-JanVrije Univ Amsterdam, Netherlands; Canc Ctr Amsterdam, Netherlands; Boelelaan 1117-1118, Netherlands (author)
Gruenberger, ThomasSigmund Freud Private Univ, Austria (author)
Vrije Univ Amsterdam, Netherlands; Canc Ctr Amsterdam, NetherlandsPoliambulanza Fdn Hosp, Italy (creator_code:org_t)

By the author/editor: Kuiper, Babette ...; Abu Hilal, Moham ...; Aldrighetti, Luc ...; Björnsson, Bergt ...; D'hondt, Mathieu; Dopazo, Cristina; show more...; Fretland, Asmund ...; Isoniemi, Helena; Jonas, J. Philip; Kazemier, Geert; Lesurtel, Mickae ...; Primrose, John; Schnitzbauer, An ...; Buffart, Tineke; Gruenberger, Bir ...; Swijnenburg, Rut ...; Gruenberger, Tho ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Surgery

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