id:"swepub:oai:DiVA.org:liu-21149"
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- Olsson, Anna,1974-Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet (författare)
Evaluation of reconstruction techniques in regional cerebral blood flow SPECT using trade-off plots : A Monte Carlo study
- Artikel/kapitelEngelska2007
Förlag, utgivningsår, omfång ...
- United States :Lippincott Williams & Wilkins,2007
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Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:liu-21149
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-21149URI
- https://doi.org/10.1097/MNM.0b013e328274204dDOI
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- Språk:engelska
- Sammanfattning på:engelska
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Klassifikation
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- BACKGROUND AND AIM: The image quality of single photon emission computed tomography (SPECT) depends on the reconstruction algorithm used. The purpose of the present study was to evaluate parameters in ordered subset expectation maximization (OSEM) and to compare systematically with filtered back-projection (FBP) for reconstruction of regional cerebral blood flow (rCBF) SPECT, incorporating attenuation and scatter correction. METHODS: The evaluation was based on the trade-off between contrast recovery and statistical noise using different sizes of subsets, number of iterations and filter parameters. Monte Carlo simulated SPECT studies of a digital human brain phantom were used. The contrast recovery was calculated as measured contrast divided by true contrast. Statistical noise in the reconstructed images was calculated as the coefficient of variation in pixel values. RESULTS: A constant contrast level was reached above 195 equivalent maximum likelihood expectation maximization iterations. The choice of subset size was not crucial as long as there were > or = 2 projections per subset. The OSEM reconstruction was found to give 5-14% higher contrast recovery than FBP for all clinically relevant noise levels in rCBF SPECT. The Butterworth filter, power 6, achieved the highest stable contrast recovery level at all clinically relevant noise levels. The cut-off frequency should be chosen according to the noise level accepted in the image. CONCLUSION: Trade-off plots are shown to be a practical way of deciding the number of iterations and subset size for the OSEM reconstruction and can be used for other examination types in nuclear medicine.
Ämnesord och genrebeteckningar
- rCBF
- SPECT (tomography
- emission-computed
- single-photon)
- image reconstruction (image processing
- computer-assisted)
- Monte Carlo (Monte Carlo method)
- MEDICINE
- MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Ärlig, ÅsaCounty Hospital Ryhov, Jönköping (författare)
- Alm Carlsson, Gudrun,1939-Östergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Hälsouniversitetet,Radiofysikavdelningen(Swepub:liu)gudal03 (författare)
- Gustafsson, AgnethaÖstergötlands Läns Landsting,Linköpings universitet,Medicinsk radiofysik,Radiofysikavdelningen,Hälsouniversitetet(Swepub:liu)agngu51 (författare)
- Linköpings universitetMedicinsk radiofysik (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Nuclear medicine communicationsUnited States : Lippincott Williams & Wilkins28:9, s. 719-7250143-36361473-5628
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- Nuclear medicine communications (Sök värdpublikationen i LIBRIS)
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