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Mammary epithelial ...
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Benn, CSDept of Epidemiology Köpenhamn, Danmark
(författare)
Mammary epithelial paracellular permeability in atopic and non-atopic mothers versus childhood atopy
- Artikel/kapitelEngelska2004
Förlag, utgivningsår, omfång ...
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Wiley,2004
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-22342
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-22342URI
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https://doi.org/10.1046/j.1399-3038.2003.00138.xDOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Sodium/potassium (Na/K) ratios are considered to be a marker of mammary epithelial paracellular permeability. The aim of the present study was to investigate the association between maternal atopy and Na/K ratios in breast milk and the association between Na/K ratios in breast milk and the development of atopy in the offspring. Early and mature milk samples were obtained from 30 atopic and 43 non-atopic women. We found no differences in the Na/K ratios between atopic and non-atopic women. At 18 months of age, 22 (30%) of the children had a positive skin prick test (SPT) and 26 (36%) had symptoms of atopic diseases. Overall, high levels of Na/K compared with low and slightly raised levels of Na/K in the maternal milk tended to be associated with a positive SPT and atopic disease. However, if the mother was atopic, high levels of Na/K in early or mature milk were associated with a significantly increased risk of a positive SPT or atopic disease in the offspring [RR = 4.8 (1.9-12)] whereas no such association was observed in non-atopic mothers [RR = 0.8 (0.4-1.7), p for interaction = 0.001]. Thus, high Na/K levels in the breast milk may be associated with the development of atopy and atopic diseases in the offspring of atopic mothers.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Fagerås Böttcher, Malin,1969-Linköpings universitet,Hälsouniversitetet,Pediatrik(Swepub:liu)malfa24
(författare)
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Pedersen, BVDept of Epidemiology Köpenhamn, Danmark
(författare)
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Filteau, SMCentre of International Child Health London, UK
(författare)
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Duchén, Karel,1961-Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Pediatrik,Barn- och ungdomskliniken i Linköping(Swepub:liu)kardu59
(författare)
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Dept of Epidemiology Köpenhamn, DanmarkHälsouniversitetet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Pediatric Allergy and Immunology: Wiley15:2, s. 123-1260905-61571399-3038
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