Sökning: WFRF:(Duchén Karel 1961 ) >
Mammary epithelial ...
Mammary epithelial paracellular permeability in atopic and non-atopic mothers versus childhood atopy
-
- Benn, CS (författare)
- Dept of Epidemiology Köpenhamn, Danmark
-
- Fagerås Böttcher, Malin, 1969- (författare)
- Linköpings universitet,Hälsouniversitetet,Pediatrik
-
- Pedersen, BV (författare)
- Dept of Epidemiology Köpenhamn, Danmark
-
visa fler...
-
- Filteau, SM (författare)
- Centre of International Child Health London, UK
-
- Duchén, Karel, 1961- (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Pediatrik,Barn- och ungdomskliniken i Linköping
-
visa färre...
-
(creator_code:org_t)
- Wiley, 2004
- 2004
- Engelska.
-
Ingår i: Pediatric Allergy and Immunology. - : Wiley. - 0905-6157 .- 1399-3038. ; 15:2, s. 123-126
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Sodium/potassium (Na/K) ratios are considered to be a marker of mammary epithelial paracellular permeability. The aim of the present study was to investigate the association between maternal atopy and Na/K ratios in breast milk and the association between Na/K ratios in breast milk and the development of atopy in the offspring. Early and mature milk samples were obtained from 30 atopic and 43 non-atopic women. We found no differences in the Na/K ratios between atopic and non-atopic women. At 18 months of age, 22 (30%) of the children had a positive skin prick test (SPT) and 26 (36%) had symptoms of atopic diseases. Overall, high levels of Na/K compared with low and slightly raised levels of Na/K in the maternal milk tended to be associated with a positive SPT and atopic disease. However, if the mother was atopic, high levels of Na/K in early or mature milk were associated with a significantly increased risk of a positive SPT or atopic disease in the offspring [RR = 4.8 (1.9-12)] whereas no such association was observed in non-atopic mothers [RR = 0.8 (0.4-1.7), p for interaction = 0.001]. Thus, high Na/K levels in the breast milk may be associated with the development of atopy and atopic diseases in the offspring of atopic mothers.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas