Food-borne outbreak of gastroenteritis associated with genogroup I calicivirus.

• An outbreak of gastroenteritis affecting 158 of 219 (72%) guests and employees at a hotel is described. Food served at the hotel restaurant is believed to have been the source of the outbreak and to have been contaminated by sick employees working in the restaurant. A secondary attack rate of 22% was seen involving 43 persons in all. In stool specimens from seven of eight patients, Norwalk-like viruses (NLVs) were detected by electron microscopy. While NLV-specific PCR using primers JV12 and JV13 were negative, all specimens examined with primers NVp69 and NVp110 were positive. The failure of primers JV12 and JV13 was attributed to several mismatches in the JV12 primer. Genotyping and sequence analysis revealed that all samples had identical sequences and clustered with genogroup I, and the most closely related well-characterized genotype is Desert Shield. This is the first described food-borne outbreak associated with genogroup I virus in Sweden.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Microbiology in the medical area (hsv//eng)

Nyckelord

Caliciviridae Infections/*epidemiology/virology

Child

Preschool

*Disease Outbreaks

Feces/virology

Food Poisoning/*epidemiology/virology

Gastroenteritis/*epidemiology/virology

Genotype

Human

Incidence

Middle Age

Non-U.S. Gov't

Support

80 and over

Caliciviridae/*classification

Aged

Adult

Adolescence

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)