Sökning: L773:1878 3503 OR L773:0035 9203 >
Kinetics of sedimen...
Kinetics of sedimentation rate, viral load and TNF-α in relation to HIV co-infection in tuberculosis
-
- Schön, Thomas, 1973- (författare)
- Linköpings universitet,Hälsouniversitetet,Medicinsk mikrobiologi
-
Wolday, Dawit (författare)
-
Elias, Daniel (författare)
-
visa fler...
-
Melese, Endalkachew (författare)
-
Mogens, Feleke (författare)
-
Tessema, Tesfaye (författare)
-
- Stendahl, Olle, 1946- (författare)
- Linköpings universitet,Hälsouniversitetet,Medicinsk mikrobiologi
-
- Sundqvist, Tommy, 1949- (författare)
- Linköpings universitet,Hälsouniversitetet,Medicinsk mikrobiologi
-
- Britton, Sven (författare)
- Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
- Oxford University Press (OUP), 2006
- 2006
- Engelska.
-
Ingår i: Transactions of the Royal Society of Tropical Medicine and Hygiene. - : Oxford University Press (OUP). - 0035-9203 .- 1878-3503. ; 100:5, s. 483-488
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- The kinetics of potential surrogate markers in HIV-positive (HIV+) and HIV-negative (HIV-), smear-positive tuberculosis (Tb+) patients in Gondar, Ethiopia (n = 60) was investigated. Clinical symptoms, sputum conversion, sedimentation rate (SR), HIV viral load and serum levels of TNF-α were determined before and 8 weeks after treatment initiation. The co-infection rate of HIV was 45%. There were significantly higher initial levels of SR and TNF-α in HIV+/Tb+ patients (79 ± 29 mm/h and 13.5 ± 7.6 pg/ml), than in HIV-/Tb+ patients (60 ± 23 mm/h and 6.8 ± 5.9 pg/ml, P < 0.001). In HIV-/Tb+ patients, there was a marked decrease in SR compared with co-infected patients (46% [33 ± 24 mm/h at week 8] vs. 24% [61 ± 27 mm/h at week 8]). The HIV viral load (4.99 [range 3.70-5.92] to 4.90 [range 3.96-5.78] log10 copies/ml from week 0 to 8) and TNF-α (13.5 ± 7.6 to 12.0 ± 6.0 pg/ml) remained high in HIV+/Tb+ patients. In Tb patients, SR was significantly increased in HIV+ compared with HIV- patients. Additionally, TNF-α and HIV viral load remained elevated in HIV+/ Tb+ patients following treatment despite clinical improvement comparable to HIV-/Tb+ patients. © 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
Nyckelord
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Schön, Thomas, 1 ...
-
Wolday, Dawit
-
Elias, Daniel
-
Melese, Endalkac ...
-
Mogens, Feleke
-
Tessema, Tesfaye
-
visa fler...
-
Stendahl, Olle, ...
-
Sundqvist, Tommy ...
-
Britton, Sven
-
visa färre...
- Artiklar i publikationen
-
Transactions of ...
- Av lärosätet
-
Linköpings universitet
-
Karolinska Institutet