Assessment of Suspected Aortic Stenosis by Auto Mutual Information Analysis of Murmurs

Ahlström, Christer,1977-Linköpings universitet,Fysiologisk mätteknik,Tekniska högskolan (författare)

Mild sclerotic thickening of the aortic valve affects 25% of the population, and the condition causes aortic valve stenosis (AS) in 2% of adults above 65 years. Echocardiography is today the clinical standard for assessing AS. However, a cost effective and uncomplicated technique that can be used for decision support in the primary health care would be of great value. In this study, recorded phonocardiographic signals were analyzed using the first local minimum of the auto mutual information (AMI) function. The AMI method measures the complexity in the sound signal, which is related to the amount of turbulence in the blood flow and thus to the severity of the stenosis. Two previously developed phonocardiographic methods for assessing AS severity were used for comparison, the murmur energy ratio and the sound spectral averaging technique. Twenty-nine patients with suspected AS were examined with Doppler echocardiography. The aortic jet velocity was used as a reference of AS severity, and it was found to correlate with the AMI method, the murmur energy ratio and the sound spectral averaging technique with the correlation coefficient R = 0.82, R = 0.73 and R = 0.76, respectively.

Ask, Per,1950-Linköpings universitet,Fysiologisk mätteknik,Tekniska högskolan(Swepub:liu)peras02 (författare)
Rask, PeterUniversity Hospital, Örebro, Sweden (författare)
Karlsson, Jan-ErikCounty Hospital Ryhov, Jönköping, Sweden (författare)
Nylander, Eva,1951-Östergötlands Läns Landsting,Linköpings universitet,Klinisk fysiologi,Hälsouniversitetet,Fysiologiska kliniken(Swepub:liu)evany41 (författare)
Dahlström, Ulf,1946-Östergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken(Swepub:liu)ulfda85 (författare)
Hult, Peter,1964-Linköpings universitet,Fysiologisk mätteknik,Tekniska högskolan(Swepub:liu)pethu44 (författare)
Linköpings universitetFysiologisk mätteknik (creator_code:org_t)

Ingår i:Engineering in Medicine and Biology Society, 2007. EMBS 2007, s. 1945-19489781424407873

Av författaren/redakt...: Ahlström, Christ ...; Ask, Per, 1950-; Rask, Peter; Karlsson, Jan-Er ...; Nylander, Eva, 1 ...; Dahlström, Ulf, ...; visa fler...; Hult, Peter, 196 ...; visa färre...

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