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NFKB and NFKBI poly...
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Sun, Xiao-Feng,1959-Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Onkologi,Onkologiska kliniken US
(författare)
NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases
- Artikel/kapitelEngelska2007
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Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-40449
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-40449URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Nuclear factor-κB (NF-κB) is responsible for the expression by regulating many genes for immune response, cell adhesion, differentiation, proliferation, angiogenesis and apoptosis. The function of NF-κB is inhibited by binding to NF-κB inhibitor (IκB), and imbalance of NF-κB and IκB has been associated with development of many diseases, including tumours. In this review, we focus on polymorphisms of the NFKB and NFKBI genes in relation to development of common inflammatory diseases including ulcerative colitis (UC), Crohn's disease (CD), rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, giant cell arthritis, type 1 diabetes, multiple sclerosis, celiac disease, and Parkinson's disease, as well as susceptibility of several cancers, such as oral squamous cell carcinoma, colorectal cancer (CRC), hepatocellular carcinoma, breast cancer and myeloma.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Zhang, Hong,1957-Linköpings universitet,Hälsouniversitetet,Avdelningen för dermatologi och venereologi(Swepub:liu)honzh78
(författare)
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Linköpings universitetHälsouniversitetet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Histology and Histopathology22:10-12, s. 1387-13980213-39111699-5848
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