Sökning: L773:0003 2670 >
Differentiation of ...
Differentiation of human serum samples by surface plasmon resonance monitoring of the integral glycoprotein interaction with a lectin panel
-
- Mecklenburg, M. (författare)
- Pure and Applied Biochemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden
-
- Svitel, Juraj (författare)
- Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Pure and Applied Biochemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden
-
- Winquist, Fredrik (författare)
- Linköpings universitet,Tekniska högskolan,Tillämpad Fysik
-
visa fler...
-
Gang, J. (författare)
-
- Ornstein, Katharina (författare)
- Lund University,Lunds universitet,Infektionsmedicin,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Infection Medicine (BMC),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Infectious Diseases, Lund University Hospital, SE-22185 Lund, Sweden
-
- Dey, Estera (författare)
- Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Pure and Applied Biochemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden
-
- Xie, Bin (författare)
- Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Pure and Applied Biochemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden
-
Hedborg, E. (författare)
-
- Norrby, R. (författare)
- Department of Infectious Diseases, Lund University Hospital, SE-22185 Lund, Sweden
-
- Arwin, H. (författare)
- Department of Infectious Diseases, Lund University Hospital, SE-22185 Lund, Sweden
-
- Lundström, Ingemar (författare)
- Linköpings universitet,Tekniska högskolan,Tillämpad Fysik
-
- Danielsson, Bengt (författare)
- Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Pure and Applied Biochemistry, Lund University, P.O. Box 124, SE-22100 Lund, Sweden
-
visa färre...
-
Pure and Applied Biochemistry, Lund University, PO. Box 124, SE-22100 Lund, Sweden Tillämpad biokemi (creator_code:org_t)
- 2002
- 2002
- Engelska.
-
Ingår i: Analytica Chimica Acta. - 0003-2670 .- 1873-4324. ; 459:1, s. 25-31
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
visa färre...
Abstract
Ämnesord
Stäng
- Bacterial infection and inflammation result in massive changes in serum glycoproteins. These changes were investigated by the interaction of the saccharide glycoprotein moiety with lectins. A panel of eight lectins (Canavalia ensiformis, Bandeiraea simplicifolia BS-I, Arachis hypogaea, Phytolacca americana, Phaseolus vulgaris, Artocarpus integrifolia, Triticum vulgaris and Pisum sativum) was used to differentiate human serum glycoproteins obtained from patients with various bacterial infections. Lectin functionalised sensing layers were created on gold-coated wafers and lectin-glycoprotein interactions were monitored by surface plasmon resonance. The interaction of the lectin panel with serum glycoproteins produces unique patterns. Principal component analysis (PCA) was used to analyse the patterns. The actual panel of eight lectins enabled discrimination between sera obtained from patients sick with bacterial infection and healthy patients. Extended lectin panels have the potential to distinguish between types of bacterial infection and identify specific disease state. © 2002 Elsevier Science B.V. All rights reserved.
Ämnesord
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
Nyckelord
- Bacterial infection
- Glycoprotein
- Human serum
- Lectin panel
- Principal component analysis
- Surface plasmon resonance
- TECHNOLOGY
- TEKNIKVETENSKAP
- Bacterial infection
- Glycoprotein
- Human serum
- Lectin panel
- Principal component analysis
- Surface plasmon resonance
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Mecklenburg, M.
-
Svitel, Juraj
-
Winquist, Fredri ...
-
Gang, J.
-
Ornstein, Kathar ...
-
Dey, Estera
-
visa fler...
-
Xie, Bin
-
Hedborg, E.
-
Norrby, R.
-
Arwin, H.
-
Lundström, Ingem ...
-
Danielsson, Beng ...
-
visa färre...
- Om ämnet
-
- NATURVETENSKAP
-
NATURVETENSKAP
-
och Kemi
-
och Analytisk kemi
- Artiklar i publikationen
-
Analytica Chimic ...
- Av lärosätet
-
Linköpings universitet
-
Lunds universitet