Search: WFRF:(Hashimoto Takehiro)
> (2010) >
An Atlas of Combina...
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Ravasi, TimothyUniversity Calif San Diego
(author)
An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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Elsevier BV,2010
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-54509
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-54509URI
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https://doi.org/10.1016/j.cell.2010.01.044DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:120105025URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Combinatorial interactions among transcription factors are critical to directing tissue-specific gene expression. To build a global atlas of these combinations, we have screened for physical interactions among the majority of human and mouse DNA-binding transcription factors (TFs). The complete networks contain 762 human and 877 mouse interactions. Analysis of the networks reveals that highly connected TFs are broadly expressed across tissues, and that roughly half of the measured interactions are conserved between mouse and human. The data highlight the importance of TF combinations for determining cell fate, and they lead to the identification of a SMAD3/FLI1 complex expressed during development of immunity. The availability of large TF combinatorial networks in both human and mouse will provide many opportunities to study gene regulation, tissue differentiation, and mammalian evolution.
Subject headings and genre
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TECHNOLOGY
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TEKNIKVETENSKAP
Added entries (persons, corporate bodies, meetings, titles ...)
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Suzuki, HarukazuUniversity Calif San Diego
(author)
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Vittorio Cannistraci, CarloUniversity Calif San Diego
(author)
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Katayama, ShintaroUniversity Calif San Diego
(author)
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Bajic, Vladimir BUniversity Calif San Diego
(author)
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Tan, KaiUniversity Calif San Diego
(author)
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Akalin, AltunaUniversity Calif San Diego
(author)
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Schmeier, SebastianUniversity Calif San Diego
(author)
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Kanamori-Katayama, MutsumiUniversity Calif San Diego
(author)
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Bertin, NicolasUniversity Calif San Diego
(author)
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Carninci, PieroUniversity Calif San Diego
(author)
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Daub, Carsten OUniversity Calif San Diego
(author)
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Forrest, Alistair R RUniversity Calif San Diego
(author)
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Gough, JulianUniversity Calif San Diego
(author)
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Grimmond, SeanUniversity Calif San Diego
(author)
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Han, Jung-HoonUniversity Calif San Diego
(author)
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Hashimoto, TakehiroUniversity Calif San Diego
(author)
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Hide, WinstonUniversity Calif San Diego
(author)
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Hofmann, OliverUniversity Calif San Diego
(author)
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Kawaji, HideyaUniversity Calif San Diego
(author)
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Kubosaki, AtsutakaUniversity Calif San Diego
(author)
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Lassmann, TimoUniversity Calif San Diego
(author)
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van Nimwegen, ErikUniversity Calif San Diego
(author)
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Ogawa, ChihiroUniversity Calif San Diego
(author)
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D Teasdale, RohanUniversity Calif San Diego
(author)
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Tegnér, JesperKarolinska Institutet,Linköpings universitet,Biologiska Beräkningar,Tekniska högskolan(Swepub:liu)jeste12
(author)
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Lenhard, BorisUniversity Calif San Diego
(author)
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A Teichmann, SarahUniversity Calif San Diego
(author)
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Arakawa, TakahiroUniversity Calif San Diego
(author)
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Ninomiya, NorikoUniversity Calif San Diego
(author)
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Murakami, KayokoUniversity Calif San Diego
(author)
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Tagami, MichihiraUniversity Calif San Diego
(author)
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Fukuda, ShiroUniversity Calif San Diego
(author)
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Imamura, KengoUniversity Calif San Diego
(author)
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Kai, ChikatoshiUniversity Calif San Diego
(author)
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Ishihara, RyokoUniversity Calif San Diego
(author)
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Kitazume, YayoiUniversity Calif San Diego
(author)
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Kawai, JunUniversity Calif San Diego
(author)
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A Hume, DavidUniversity Calif San Diego
(author)
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Ideker, TreyUniversity Calif San Diego
(author)
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Hayashizaki, YoshihideUniversity Calif San Diego
(author)
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University Calif San DiegoBiologiska Beräkningar
(creator_code:org_t)
Related titles
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In:CELL: Elsevier BV140:5, s. 744-7520092-86741097-4172
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Ravasi, Timothy
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Suzuki, Harukazu
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Vittorio Cannist ...
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Katayama, Shinta ...
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Bajic, Vladimir ...
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Tan, Kai
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Akalin, Altuna
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Schmeier, Sebast ...
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Kanamori-Katayam ...
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Bertin, Nicolas
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Carninci, Piero
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Daub, Carsten O
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Forrest, Alistai ...
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Gough, Julian
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Grimmond, Sean
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Han, Jung-Hoon
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Hashimoto, Takeh ...
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Hide, Winston
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Hofmann, Oliver
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Kawaji, Hideya
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Kubosaki, Atsuta ...
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Lassmann, Timo
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van Nimwegen, Er ...
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Ogawa, Chihiro
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D Teasdale, Roha ...
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Tegnér, Jesper
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Lenhard, Boris
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A Teichmann, Sar ...
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Arakawa, Takahir ...
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Ninomiya, Noriko
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Murakami, Kayoko
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Tagami, Michihir ...
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Fukuda, Shiro
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Imamura, Kengo
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Kai, Chikatoshi
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Ishihara, Ryoko
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Kitazume, Yayoi
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Kawai, Jun
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A Hume, David
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Ideker, Trey
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Hayashizaki, Yos ...
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CELL
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Linköping University
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Karolinska Institutet