Sökning: WFRF:(Derwinger Kristoffer 1969)
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Age Aspects of Demo...
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Derwinger, Kristoffer,1969Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Sahlgrens University Hospital
(författare)
Age Aspects of Demography, Pathology and Survival Assessment in Colorectal Cancer
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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International Institute of Anticancer Research,2010
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-66327
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-66327URI
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https://gup.ub.gu.se/publication/132582URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Aim: The aim of this study was to assess how age is related to differences in stage, tumour differentiation and treatment in colorectal cancer. Patients and Methods: A retrospective study in a consecutive series of colorectal cancer patients (n=2220) where age was related to demography, stage, tumour characteristics, treatment and outcome (OS/CSS) both as a continuous variable and grouped by high/low 10th percentiles, as young/old groups, with a third median reference group. Results: Young patients had more advanced cancer stages (p=0.012), higher N-status (p=0.011) and more frequent T4/G4 tumours. Old patients had higher postoperative mortality and were less likely to receive chemotherapy. The proportion of cancer-related deaths was stage-dependent and decreased with age. Conclusion: Cancer stage, tumour characteristics, treatment and outcome can vary with age in colorectal cancer. The increasing proportion of non-cancer deaths at a higher age can affect the use of overall survival as an outcome parameter, which may be of importance in evaluating clinical and translational research.
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Kodeda, KarlGothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Sahlgrens University Hospital(Swepub:gu)xkodka
(författare)
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Gerjy, RogerÖstergötlands Läns Landsting,Linköpings universitet,Kirurgi,Hälsouniversitetet,Kirurgiska kliniken i Östergötland med verksamhet i Linköping, Norrköping och Motala(Swepub:liu)rogge32
(författare)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för kirurgi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:ANTICANCER RESEARCH: International Institute of Anticancer Research30:12, s. 5227-52310250-70051791-7530
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