Health-related quality of life in patients with cryptogenic polyneuropathy compared with the general population

Purpose. To evaluate the quality of life (QOL) in patients with cryptogenic polyneuropathy. Method. Two validated instruments (SF-36 and EQ-5D) were sent to 86 patients with a 72% response rate (44 men, 18 women). As reference, 2721 individuals (1292 men, 1429 women; 59% response rate) from the general population responded to the same QOL instruments. Results. Compared to the general population, QOL was significantly more affected in patients with polyneuropathy concerning motor functions, with 42% of the patients reporting problems with walking, 7% having difficulties with washing and dressing, and 31% having problems with usual activities (work, study, household work, and family or leisure activities). The EQ-5D results showed that 85% of the patients were suffering from pain compared to 56% of the general population. Mental health was preserved among patients with polyneuropathy. Mobility was declining with increasing age in patients, but was not affected by disease duration. Conclusions. Our study showed that patients with cryptogenic polyneuropathy have a lower QOL compared to the general population, although mental health scores did not differ between the groups. This information may be helpful when explaining the disease and its impact on newly diagnosed patients.

Tondel, Martin,1962Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,University of Gothenburg(Swepub:gu)xtonma (författare)
Persson, BodilÖstergötlands Läns Landsting,Linköpings universitet,Yrkes- och miljömedicin,Hälsouniversitetet,Arbets- och miljömedicin(Swepub:liu)bodpe23 (författare)
Vrethem, MagnusÖstergötlands Läns Landsting,Linköpings universitet,Neurologi,Hälsouniversitetet,Neurologiska kliniken(Swepub:liu)magvr07 (författare)
Ryhov County HospitalInstitutionen för medicin, avdelningen för samhällsmedicin och folkhälsa (creator_code:org_t)

Ingår i:DISABILITY AND REHABILITATION: Informa Healthcare33:7, s. 617-6230963-82881464-5165

Av författaren/redakt...: Lindh, Jonas; Tondel, Martin, ...; Persson, Bodil; Vrethem, Magnus

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Neurologi

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