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A meta-analysis of ...
A meta-analysis of the efficacy of wound catheters for post-operative pain management
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- Gupta, Anil (author)
- Östergötlands Läns Landsting,Linköpings universitet,Anestesiologi med intensivvård,Hälsouniversitetet,Anestesi- och operationkliniken US
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- Favaios, S. (author)
- EPE
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- Perniola, A. (author)
- Orebro University Hospital
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- Magnuson, A. (author)
- University Orebro
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- Berggren, L. (author)
- Orebro University Hospital
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(creator_code:org_t)
- 2011-05-25
- 2011
- English.
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In: Acta Anaesthesiologica Scandinavica. - : Blackwell Publishing Ltd. - 0001-5172 .- 1399-6576. ; 55:7, s. 785-796
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Local anesthetics (LA) are injected via catheters placed in surgical wounds for post-operative analgesia. The primary aim of this systematic review was to assess whether LA reduce pain intensity when injected via wound catheters. A literature search was performed from Medline via PubMed, EMBASE and the Cochrane database from 1966 until November 2009. The search strategy included the following key words: pain, postoperative, catheters and local anesthetics. Two co-authors independently read every article that was initially included and extracted data into a pre-defined study record form. A total of 753 studies primarily fit the search criteria and 163 were initially extracted. Of these, 32 studies were included in the meta-analysis. Wound catheters provided no significant analgesia at rest or on activity, except in patients undergoing gynecological and obstetric surgery at 48 h (P = 0.03). The overall morphine consumption was lower (approximate to 13 mg) during 0-24 h (P less than 0.001) in these patients. No significant differences in side effects were found, except for a lower risk of wound breakdown (P = 0.048) and a shorter length of hospital stay (P = 0.04) in patients receiving LA. A statistically significant heterogeneity was seen between the studies in most end-points. LA injected via wound catheters did not reduce pain intensity, except at 48 h in a subgroup of patients undergoing obstetric and gynecological surgery. Rescue analgesic consumption was also lower in this group at 0-24 h. The magnitude of these effects was small and compounded by pronounced heterogeneity.
Keyword
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- for (subject category)
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